1st Optimal vs LIV by WellNow
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
1st Optimal
Best for Patients wanting GLP-1 therapy within a lab-driven functional-medicine programLIV by WellNow
Best for Patients in IL, IN, MI, NY, or PA wanting flat all-inclusive compounded semaglutideStarting at $279/mo
Side-by-Side Comparison
| Feature | 1st Optimal | LIV by WellNow |
|---|---|---|
| Overall Score | 6.7/10 | ✓6.8/10 |
| Starting Price | — | $279/mo |
| Editorial Rating | 3.4 ★ /5 | 3.4 ★ /5 |
| Features | 8 features | 8 features |
| States Available | 0 | ✓5 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
1st Optimal
Pros
- ✓Offers both semaglutide and tirzepatide with injectable and oral formats
- ✓Functional-medicine approach with at-home labs and blood-work interpretation
- ✓Unlimited coaching and ongoing support included
- ✓No long-term contracts
- ✓Board-certified doctors and nurse practitioners referenced
Cons
- ✗No public monthly pricing disclosed
- ✗No published state availability list
- ✗Compounded vs branded sourcing not clarified on site
- ✗Pricing only revealed after quiz or consultation
LIV by WellNow
Pros
- ✓Flat $279/month covers medication, supplies, and unlimited virtual visits
- ✓Backed by established WellNow Urgent Care brand
- ✓Board-certified online medical providers
- ✓Same-day approval and monthly home delivery
- ✓Transparent all-inclusive pricing with no hidden fees
Cons
- ✗Compounded semaglutide is not FDA-approved or evaluated
- ✗Only available in five states (IL, IN, MI, NY, PA)
- ✗No tirzepatide option offered
- ✗Insurance not accepted for compounded semaglutide
Our Verdict
LIV by WellNow edges out 1st Optimal with a higher overall score of 6.8/10 and is particularly strong for Patients in IL, IN, MI, NY, or PA wanting flat all-inclusive compounded semaglutide. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring 1st Optimal and LIV by WellNow head-to-heads in the same category.
- 1st Optimal vs CoreAge Rx
- 1st Optimal vs TrimRx
- 1st Optimal vs Amazon One Medical
- LIV by WellNow vs NovoCare Pharmacy
- LIV by WellNow vs Vytora Health
- LIV by WellNow vs Enhance MD
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.