Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

1st Optimal vs Kina

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Kina logo

Kina

7.8
★★★3.9/5

Best for: GLP-1 weight care alongside HRT, from board-certified physicians

Visit Kina

1st Optimal and Kina are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Kina starts at $179/mo, and Kina edges ahead overall (7.8 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Pricing not publicly listed.

Kina

StartingCompounded
$179/mo
semaglutide

GLP-1 program from $179/mo (Kina lists 'GLP-1 Treatment starting at $179/month'); +$50 physician consult, $0 membership; $100 off first month promo. FSA/HSA eligible.

StartingCompounded
$179/mo
tirzepatide

$179/mo is the GLP-1 program starting price (compounded tirzepatide also offered); exact tirzepatide pricing confirmed at intake. +$50 consult.

Get alerted when GLP-1 prices drop

Join the GLP-1 price-watch list — we re-verify 440+ providers' prices on their own sites and email you when tracked prices move.

What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Kina

What the monthly price covers

Medication

Included

Provider visits

Billed separately

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Kina

7.8/10

Value25%

6.5A
vs
B
7.5

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

6.5A
vs
B
8.5

Trust & Safety15%

6.5A
vs
B
8.0

Accessibility10%

6.5A
vs
B
6.5

Support10%

7.4A
vs
B
8.0

Features & Coverage

Feature1st OptimalKina
Starting Price$179/mo
Features8 features8 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Kina

Kina is a menopause-care telehealth platform where GLP-1 is the weight-loss treatment, offered alongside HRT, peptide, and compounded options for menopause symptoms. Its GLP-1 program provides compounded semaglutide and tirzepatide from $179/month (plus a $50 physician consult; $0 membership), prescribed and monitored by board-certified physicians at Arora Health & Aesthetics. It carries verifiable LegitScript certification, is FSA/HSA eligible, ships free, and is cancel-anytime. Compounded medications are not FDA-approved; the pharmacy is not named.

Read our full Kina review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Kina

What we like

  • Menopause-specialized care — GLP-1 weight treatment alongside HRT, peptide, and compounded options for menopause symptoms
  • Prescribed and monitored by named board-certified physicians at Arora Health & Aesthetics, with dose adjustments included
  • Verifiable LegitScript certification (seal ID 50917967)
  • GLP-1 from $179/month with $0 membership fees, FSA/HSA eligibility, free shipping, and cancel-anytime
  • Compounded semaglutide and tirzepatide, 100% online with a roughly 2-minute intake

Watch-outs

  • Compounded medications are not FDA-approved — not brand Wegovy, Ozempic, Zepbound, or Mounjaro
  • Built for women navigating menopause — less tailored if that is not your situation
  • A separate $50 physician consultation fee applies on top of the medication price
  • The compounding pharmacy partner is not named, and the full list of served states is not published

Our Verdict

Winner: Kina

Kina edges out 1st Optimal with a higher overall score of 7.8/10 and is particularly strong for GLP-1 weight care alongside HRT, from board-certified physicians. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program.

Choose Kina if…

You want GLP-1 weight care alongside HRT, from board-certified physicians and a starting price around $179/mo.

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online.

No insurance needed · vetted by our editors

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

7.6

RNK Health

Compounded GLP-1 alongside NAD+, peptide and longevity add-ons

6.2

Wellorithm

Compounded GLP-1 access with oral tablet options across 49 states

7.6

SkinnyRx

Mainstream telehealth GLP-1 access

1st Optimal vs Kina: FAQ

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring 1st Optimal and Kina head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.