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1st Optimal vs KIN Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal →
VS
KIN Health logo

KIN Health

7.8
★★★★☆3.9/5

Best for: flat-price compounded GLP-1 with named pharmacies and no membership fee

Visit KIN Health →

1st Optimal and KIN Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $169/mo, and KIN Health edges ahead overall (7.8 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

KIN Health

Month-to-month, same price at every dose (0.25 mg to 2.4 mg)Compounded
$169/mo
semaglutide

Flat at all five doses. Charged at checkout; each refill needs your approval.

Month-to-month, same price at every dose (2.5 mg to 15 mg)Compounded
$199/mo
tirzepatide

Flat at all six doses on the site; the terms say the price can change with dose.

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What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

KIN Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

KIN Health

7.8/10

Value25%

6.5A
vs
B
8.5

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

6.5A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
7.2

Accessibility10%

6.5A
vs
B
7.5

Support10%

7.4A
vs
B
6.5

Features & Coverage

Feature1st OptimalKIN Health
Starting Price✓$99/mo$169/mo
Features8 features8 features
States AvailableNot disclosed46
Compounded—✓ Yes
Brand Name✓ Yes—
FSA/HSA Accepted——
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About KIN Health

KIN Health prescribes compounded semaglutide at $169/mo and compounded tirzepatide at $199/mo, one price at every dose, with the provider review, messaging and shipping included and no membership fee. Prescribers are contracted through MD Integrations, and the dispensing pharmacies are named: Strive, Boothwyn and Drug Crafters. Each month is paid for separately, with no long plan to sign. Sermorelin, NAD+ and PT-141 are sold on the same account.

Read our full KIN Health review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

KIN Health

What we like

  • One flat price at every dose: $169/mo semaglutide and $199/mo tirzepatide, shown on the product page before any quiz
  • Provider review, ongoing messaging and shipping are included, with no membership fee and no separate consultation charge
  • Names who does the work: prescribers through MD Integrations and three pharmacies, Strive, Boothwyn and Drug Crafters
  • Publishes a provider directory with license numbers for the states that require it
  • Month-to-month: each refill needs your approval, and you are refunded in full if a provider does not approve treatment
  • The company behind it is named: KIN Medical, Inc., a Delaware corporation
  • Sermorelin, NAD+ and PT-141 on the same account, each in injection, nasal spray or dissolvable tablet form

Watch-outs

  • The terms say tirzepatide's monthly cost may change as your dose rises, which cuts against the flat-price promise on the product page
  • Product pages say no subscriptions and no auto-renew, while the terms describe a GLP-1 subscription billed each refill cycle
  • No refunds once medication ships, and a refill already sent to the pharmacy cannot be canceled
  • GLP-1 care is not offered in California, Louisiana, Minnesota or Mississippi
  • Support is by email only, with replies promised within one business day; no phone number is published
  • Claims LegitScript certification, but no record could be confirmed in LegitScript's public directory
  • Compounded semaglutide and tirzepatide are not FDA-approved, and the formula may include glycine or B12 depending on the pharmacy
  • A young brand: its terms took effect in April 2026, so there is little track record to judge

Our Verdict

Winner: KIN Health

KIN Health edges out 1st Optimal with a higher overall score of 7.8/10 and is particularly strong for flat-price compounded GLP-1 with named pharmacies and no membership fee. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose KIN Health if…

You want flat-price compounded GLP-1 with named pharmacies and no membership fee and a starting price around $169/mo.

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8.0

Sesame Care

Brand-name GLP-1s at cash prices, no compounding

8.3

Collective

The lowest flat medication price if you can absorb an annual membership fee

7.3

Sunlight

Compounded GLP-1 with unlimited telehealth visits and free shipping

1st Optimal vs KIN Health: FAQ

1st Optimal is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $169/mo for KIN Health. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
KIN Health scores higher overall at 7.8/10 versus 6.7/10, and is particularly strong for flat-price compounded GLP-1 with named pharmacies and no membership fee. That said, 1st Optimal is a better fit if you want GLP-1 therapy within a lab-driven functional-medicine program.
KIN Health lists availability in 46 states, while 1st Optimal's state list is not publicly listed.
Neither 1st Optimal nor KIN Health is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, 1st Optimal is cheaper at $99/mo versus $169/mo at KIN Health.

Key terms, explained

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Continue exploring 1st Optimal and KIN Health head-to-heads in the same category.

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