Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

1st Optimal vs Gatlan

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Gatlan logo

Gatlan

6.9
★★★3.5/5

Best for: named clinical leadership with Dr. Robert Lufkin as Chief Medical Advisor

Visit Gatlan

1st Optimal and Gatlan are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts at $99/mo, and Gatlan edges ahead overall (6.9 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Gatlan

Pricing not publicly listed.

Get alerted when GLP-1 prices drop

Join the GLP-1 price-watch list — we re-verify 500+ providers' prices on their own sites and email you when tracked prices move.

What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Gatlan

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Gatlan

6.9/10

Value25%

6.5A
vs
B
6.0

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
8.0

Accessibility10%

6.5A
vs
B
7.0

Support10%

7.4A
vs
B
7.0

Features & Coverage

Feature1st OptimalGatlan
Starting Price$99/mo
Features8 features4 features
States AvailableNot disclosed44
Compounded
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Gatlan

Gatlan is a telehealth platform offering compounded tirzepatide for weight management, positioned around "doctor-level care, minus the friction." Its standout feature is named clinical leadership — Chief Medical Advisor Dr. Robert Lufkin, a professor at UCLA/USC School of Medicine — uncommon in a market that usually hides its clinicians. The fully online process includes concierge delivery and monitoring across 44 states; pricing is shown after intake.

Read our full Gatlan review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Gatlan

What we like

  • Named Chief Medical Advisor with verifiable credentials — Dr. Robert Lufkin, UCLA/USC professor — rare in this market
  • 44 states explicitly listed — you can confirm coverage without starting the sign-up flow
  • 'Doctor-Level Care, Minus the Friction' positioning targets buyers wanting premium clinical attention
  • Fully online process with concierge delivery and monitoring
  • Compounded tirzepatide confirmed

Watch-outs

  • Pricing not shown publicly — fully gated behind the sign-up flow
  • Unclear whether compounded semaglutide is offered — only tirzepatide is mentioned on the site
  • LegitScript certification status not disclosed
  • 503A/503B pharmacy partner not named, and designation not specified
  • No compounded-medication disclaimer published
  • Corporate legal entity and physical address not disclosed
  • Refund/cancellation policy not detailed publicly
  • 7 states excluded (AK, AR, MA, NM, OR, RI, SC)

Our Verdict

Winner: Gatlan

Gatlan edges out 1st Optimal with a higher overall score of 6.9/10 and is particularly strong for named clinical leadership with Dr. Robert Lufkin as Chief Medical Advisor. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Gatlan if…

You want named clinical leadership with Dr. Robert Lufkin as Chief Medical Advisor.

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online.

No insurance needed · vetted by our editors

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

7.6

RNK Health

Compounded GLP-1 alongside NAD+, peptide and longevity add-ons

6.2

Wellorithm

Compounded GLP-1 access with oral tablet options across 49 states

7.6

SkinnyRx

Mainstream telehealth GLP-1 access

1st Optimal vs Gatlan: FAQ

1st Optimal lists a lowest ongoing price of $99/mo, while Gatlan does not publicly list one. See the side-by-side pricing above for the full breakdown.
Gatlan scores higher overall at 6.9/10 versus 6.7/10, and is particularly strong for named clinical leadership with Dr. Robert Lufkin as Chief Medical Advisor. That said, 1st Optimal is a better fit if you want GLP-1 therapy within a lab-driven functional-medicine program.
Gatlan lists availability in 44 states, while 1st Optimal's state list is not publicly listed.
Neither 1st Optimal nor Gatlan is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring 1st Optimal and Gatlan head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.