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1st Optimal vs Freya Meds

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Freya Meds logo

Freya Meds

7.0
★★★3.5/5

Best for: patients wanting dietitian-supported compounded GLP-1 programs

Visit Freya Meds

1st Optimal and Freya Meds are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $250/mo, and Freya Meds edges ahead overall (7.0 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Freya Meds

Semaglutide (quarterly billing)Compounded
$250/mo
semaglutide
Semaglutide (monthly billing)Compounded
$297/mo
semaglutide
Tirzepatide (quarterly billing)Compounded
$332/mo
tirzepatide
Tirzepatide (monthly billing)Compounded
$390/mo
tirzepatide

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What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Freya Meds

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Freya Meds

7.0/10

Value25%

6.5A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
7.3

Accessibility10%

6.5A
vs
B
7.0

Support10%

7.4A
vs
B
7.0

Features & Coverage

Feature1st OptimalFreya Meds
Starting Price$99/mo$250/mo
Features8 features5 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Freya Meds

Freya Meds is a GLP-1 specialist offering compounded semaglutide ($250–$297/mo) and compounded tirzepatide ($332–$390/mo). Includes unlimited doctor consultations, monthly group calls, and dietitian consultation. Claims 450,000+ enrolled.

Read our full Freya Meds review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Freya Meds

What we like

  • GLP-1 specialist — not a multi-category telehealth
  • Price includes unlimited doctor consultations, monthly group calls, and a dietitian consultation
  • Both semaglutide and tirzepatide available
  • Multi-month discount on quarterly billing
  • Claims 450,000+ enrolled

Watch-outs

  • No visible LegitScript or PCAB accreditation
  • Above-average pricing ($250–$390/mo)
  • Compounded only — no brand-name options
  • Now serves 49 U.S. states (one state excluded; specific exclusion not named)

Our Verdict

Winner: Freya Meds

Freya Meds edges out 1st Optimal with a higher overall score of 7.0/10 and is particularly strong for patients wanting dietitian-supported compounded GLP-1 programs. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Freya Meds if…

You want patients wanting dietitian-supported compounded GLP-1 programs and a starting price around $250/mo.

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1st Optimal vs Freya Meds: FAQ

1st Optimal is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $250/mo for Freya Meds. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Freya Meds scores higher overall at 7.0/10 versus 6.7/10, and is particularly strong for patients wanting dietitian-supported compounded GLP-1 programs. That said, 1st Optimal is a better fit if you want GLP-1 therapy within a lab-driven functional-medicine program.
Neither 1st Optimal nor Freya Meds publicly lists its exact state availability. Most national GLP-1 telehealth providers operate in the majority of states — confirm your state is covered during sign-up.
Neither 1st Optimal nor Freya Meds is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, 1st Optimal is cheaper at $99/mo versus $250/mo at Freya Meds.

Key terms, explained

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Continue exploring 1st Optimal and Freya Meds head-to-heads in the same category.

Or see the full category ranking.

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