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1st Optimal vs FormidableMD

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
FormidableMD logo

FormidableMD

7.1
★★★3.6/5

Best for: Florida patients wanting transparent, dose-based GLP-1 pricing with no membership and pay-per-visit care

Visit FormidableMD

1st Optimal and FormidableMD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, FormidableMD starts at $169/mo, and FormidableMD edges ahead overall (7.1 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Pricing not publicly listed.

FormidableMD

1mgCompounded
$169/mo
semaglutide

Dose-tiered: 1mg $169, 2mg $189, 5mg $209, 10mg $269/mo. Compounded or FDA-approved options. Separate $199 initial consult + $99 follow-up visits

10mgCompounded
$199/mo
tirzepatide

Dose-tiered: 10mg $199, 20mg $239, 30mg $279, 40mg $319/mo. Compounded or FDA-approved. Plus $199 initial consult + $99 follow-ups

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What’s included

1st Optimal

Inclusions not disclosed.

FormidableMD

What the monthly price covers

Medication

Included

Provider visits

Billed separately

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

FormidableMD

7.1/10

Value25%

6.5A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

6.5A
vs
B
7.5

Trust & Safety15%

6.5A
vs
B
7.0

Accessibility10%

6.5A
vs
B
5.0

Support10%

7.4A
vs
B
7.5

Features & Coverage

Feature1st OptimalFormidableMD
Starting Price$169/mo
Features8 features6 features
States AvailableNot disclosed1
Compounded✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About FormidableMD

FormidableMD is a physician-led, cash-pay telehealth practice based in Florida offering GLP-1 weight-loss treatment — semaglutide and tirzepatide in both FDA-approved and compounded forms, plus oral options — alongside peptides, HRT/TRT, urgent care, labs, and nutrition coaching. There is no membership or commitment: patients pay $199 for the initial consultation and $99 per follow-up, with medication priced by dose (semaglutide from $169/mo, tirzepatide from $199/mo). Compounded medications are sourced from 503A pharmacies, and visits are FSA/HSA eligible.

Read our full FormidableMD review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

FormidableMD

What we like

  • Transparent, published dose-by-dose pricing for semaglutide ($169-$269/mo) and tirzepatide ($199-$319/mo) with no membership or commitment
  • Offers both FDA-approved and compounded GLP-1s (plus oral options) from 503A pharmacies, with a real provider at every visit
  • Boutique physician-led model bundling labs, peptides, HRT/TRT and urgent care; FSA/HSA eligible

Watch-outs

  • Florida-focused telehealth — availability outside FL is not advertised, so out-of-state access is uncertain
  • Medication cost is on top of a $199 initial consultation and $99 follow-up visits (pay-per-visit, not an all-in monthly price)
  • The 503A compounding pharmacy partner is not named on the site

Our Verdict

Winner: FormidableMD

FormidableMD edges out 1st Optimal with a higher overall score of 7.1/10 and is particularly strong for Florida patients wanting transparent, dose-based GLP-1 pricing with no membership and pay-per-visit care. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose FormidableMD if…

You want Florida patients wanting transparent, dose-based GLP-1 pricing with no membership and pay-per-visit care and a starting price around $169/mo.

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1st Optimal vs FormidableMD: FAQ

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