Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

1st Optimal vs FormBlends

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
FormBlends logo

FormBlends

7.2
★★★3.6/5

Best for: Shoppers wanting a low compounded-semaglutide entry price with lots of on-site education

Visit FormBlends

1st Optimal and FormBlends are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, FormBlends starts at $99/mo, and FormBlends edges ahead overall (7.2 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Pricing not publicly listed.

FormBlends

Compounded semaglutideCompounded
$99/mo
semaglutide

Published offer price via rx.formscripts.com; may be intro — confirm at checkout

Compounded tirzepatideCompounded
$349/mo
tirzepatide

Published offer price via rx.formscripts.com

Get alerted when GLP-1 prices drop

Join the GLP-1 price-watch list — we re-verify 390+ providers' prices on their own sites and email you when tracked prices move.

What’s included

1st Optimal

Inclusions not disclosed.

FormBlends

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

FormBlends

7.2/10

Value25%

6.5A
vs
B
7.5

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
6.5

Accessibility10%

6.5A
vs
B
7.0

Support10%

7.4A
vs
B
7.0

Features & Coverage

Feature1st OptimalFormBlends
Starting Price$99/mo
Features8 features6 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About FormBlends

FormBlends is a US direct-to-consumer brand selling compounded GLP-1 weight-loss medication — compounded semaglutide from $99 and compounded tirzepatide from $349 — dispensed by a licensed 503A pharmacy and fulfilled through its FormScripts telehealth portal. The product funnel sits alongside heavy educational content and an on-site provider-comparison directory. Physician-supervised, with free shipping on orders over $150.

Read our full FormBlends review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

FormBlends

What we like

  • Low published entry price on compounded semaglutide ($99) from a licensed 503A pharmacy
  • Physician-supervised program with 24/7 care-team access and free shipping over $150
  • Extensive free educational content, guides and provider comparisons on-site

Watch-outs

  • Enrollment and final pricing complete on an external portal (rx.formscripts.com), not fully on-site
  • $99 may be an intro rate; tirzepatide is comparatively high at $349/mo
  • State availability and LegitScript status not published; pharmacy is its own FormScripts brand

Our Verdict

Winner: FormBlends

FormBlends edges out 1st Optimal with a higher overall score of 7.2/10 and is particularly strong for Shoppers wanting a low compounded-semaglutide entry price with lots of on-site education. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose FormBlends if…

You want Shoppers wanting a low compounded-semaglutide entry price with lots of on-site education and a starting price around $99/mo.

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online.

No insurance needed · vetted by our editors

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

7.7

Synergy Rx

Broadest drug catalog in the Lion MD white-label cluster

7.6

SkinnyRx

Mainstream telehealth GLP-1 access

7.8

Embody

Low flat-rate compounded GLP-1 pricing at every dose

1st Optimal vs FormBlends: FAQ

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring 1st Optimal and FormBlends head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.