1st Optimal vs ElitePhysiqMD
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
ElitePhysiqMD
Best for: compounded GLP-1 from $145/mo with peptide options, HSA/FSA eligible
Visit ElitePhysiqMD →1st Optimal and ElitePhysiqMD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $145/mo, and ElitePhysiqMD edges ahead overall (7.2 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Care membership only — the GLP-1 medication is billed separately and is not priced.
ElitePhysiqMD
Compounded semaglutide injection subscription. A $49 required telehealth visit is added per order.
Compounded tirzepatide injection subscription. A $49 required telehealth visit is added per order.
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
ElitePhysiqMD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
ElitePhysiqMD
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | ElitePhysiqMD |
|---|---|---|
| Starting Price | ✓$99/mo | $145/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About ElitePhysiqMD
ElitePhysiqMD is a physician-led telehealth platform prescribing compounded semaglutide (from $145/mo) and tirzepatide (from $315/mo subscription) to patients in all 50 states. Board-certified physicians conduct online assessments; medications ship from US-licensed 503A/503B compounding pharmacies in 5–7 business days. Also offers peptide therapy (NAD+, sermorelin, CJC-1295/ipamorelin, GHK-Cu, glutathione), TRT, and ED treatments. LegitScript certified, HIPAA-compliant, HSA/FSA eligible. Founded 2025.
Read our full ElitePhysiqMD review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
ElitePhysiqMD
What we like
- Compounded semaglutide from $145/mo subscription with no video calls and cancel-anytime policy
- LegitScript certified, HIPAA-compliant; prescriptions from board-certified physicians via 5-min online assessment
- Medications from US-licensed 503A/503B compounding pharmacies, shipped discreetly in 5–7 business days
- HSA/FSA eligible; accepts all 50 states with no insurance required
- Peptide therapy also available: NAD+, sermorelin, CJC-1295/ipamorelin, GHK-Cu, and glutathione
Watch-outs
- Required $49 telehealth visit is added to every order, increasing effective monthly cost above the headline price
- No labs disclosed; medication plans don't appear to include bloodwork or baseline testing
- No dietitian, coaching, or nutrition support mentioned; program is medication-only
- Tirzepatide subscription price ($315/mo) is above the mid-range for compounded tirzepatide
- Newer platform (founded late 2025); no Trustpilot rating or public patient reviews found
Our Verdict
ElitePhysiqMD edges out 1st Optimal with a higher overall score of 7.2/10 and is particularly strong for compounded GLP-1 from $145/mo with peptide options, HSA/FSA eligible. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.
Choose ElitePhysiqMD if…
You want compounded GLP-1 from $145/mo with peptide options, HSA/FSA eligible and a starting price around $145/mo.
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Gala
Compounded GLP-1/GIP combo on a yearly plan with free shipping
From $149/mo
Get started →TMates
Nationwide compounded GLP-1 availability including Puerto Rico
From $249/mo
Get started →Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →1st Optimal vs ElitePhysiqMD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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