1st Optimal vs Eclipse Medical Wellness
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for Patients wanting GLP-1 therapy within a lab-driven functional-medicine programEclipse Medical Wellness
Best for Colorado residents wanting clinician-led GLP-1 care with labs (medication billed separately)Side-by-Side Comparison
| Feature | 1st Optimal | Eclipse Medical Wellness |
|---|---|---|
| Overall Score | 6.7/10 | ✓7.0/10 |
| Starting Price | — | — |
| Editorial Rating | 3.4 ★ /5 | ✓3.5 ★ /5 |
| Features | 8 features | 8 features |
| States Available | 0 | ✓1 |
| Compounded | — | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Eclipse Medical Wellness
What we like
- Clinician-led care with baseline and quarterly lab monitoring included
- Prescribes FDA-approved brand GLP-1 (Wegovy, Zepbound); compounded options also available
- Transparent care-plan pricing ($749 3-month starter, ~$149/mo ongoing) with nutrition support
- Includes a prior-authorization attempt plus dose-adjustment and side-effect monitoring
Watch-outs
- Colorado residents only
- Care-plan fees are separate from medication — you pay for the drug at your pharmacy
- Prescription is not guaranteed (depends on clinical evaluation)
- Small practice; no Terms or Privacy pages found on the site
Our Verdict
Eclipse Medical Wellness edges out 1st Optimal with a higher overall score of 7.0/10 and is particularly strong for Colorado residents wanting clinician-led GLP-1 care with labs (medication billed separately). 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.