1st Optimal vs Eclipse Medical Wellness
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
Eclipse Medical Wellness
Best for: clinician-led GLP-1 care with labs (medication billed separately)
Visit Eclipse Medical Wellness →1st Optimal and Eclipse Medical Wellness are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Eclipse Medical Wellness edges ahead overall (7.0 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Eclipse Medical Wellness
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Billed separately
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Eclipse Medical Wellness
7.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Eclipse Medical Wellness |
|---|---|---|
| Starting Price | — | — |
| Features | 8 features | 8 features |
| States Available | Not disclosed | 1 |
| Compounded | — | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Eclipse Medical Wellness
Eclipse Medical Wellness is a Colorado-only, clinician-led telehealth weight-loss program. Care plans ($749 for a 3-month starter, about $149/mo ongoing) include a medical evaluation, baseline and quarterly lab monitoring, prescription management, a prior-authorization attempt, and nutrition support — but the medication itself is prescribed to your pharmacy and paid separately. It prescribes FDA-approved brand GLP-1s (Wegovy, Zepbound) plus metformin and naltrexone/bupropion, with compounded options also available. Prescription depends on clinical evaluation and is not guaranteed.
Read our full Eclipse Medical Wellness review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Eclipse Medical Wellness
What we like
- Clinician-led care with baseline and quarterly lab monitoring included
- Prescribes FDA-approved brand GLP-1 (Wegovy, Zepbound); compounded options also available
- Transparent care-plan pricing ($749 3-month starter, ~$149/mo ongoing) with nutrition support
- Includes a prior-authorization attempt plus dose-adjustment and side-effect monitoring
Watch-outs
- Colorado residents only
- Care-plan fees are separate from medication — you pay for the drug at your pharmacy
- Prescription is not guaranteed (depends on clinical evaluation)
- Small practice; no Terms or Privacy pages found on the site
Our Verdict
Eclipse Medical Wellness edges out 1st Optimal with a higher overall score of 7.0/10 and is particularly strong for clinician-led GLP-1 care with labs (medication billed separately). 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program.
Choose Eclipse Medical Wellness if…
You want clinician-led GLP-1 care with labs (medication billed separately).
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Get started →1st Optimal vs Eclipse Medical Wellness: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.