1st Optimal vs ClickSlim
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
1st Optimal and ClickSlim are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $349/mo, and 1st Optimal edges ahead overall (6.7 vs 6.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Care membership only — the GLP-1 medication is billed separately and is not priced.
ClickSlim
Introductory $299/month then $349 per month. A higher tier runs $349 introductory then $399.
Introductory $498 then $548 per month; NAD+ discounted to $199 inside the bundle.
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
ClickSlim
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
ClickSlim
6.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | ClickSlim |
|---|---|---|
| Starting Price | ✓$99/mo | $349/mo |
| Features | ✓8 features | 3 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About ClickSlim
Wyoming-registered telehealth selling compounded tirzepatide and NAD+ on introductory rates that step up after the first month, with no published state list.
Read our full ClickSlim review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
ClickSlim
What we like
- Both the introductory and the ongoing price are published, so the step-up is visible before you buy
- States plainly that it is not a pharmacy or a drug manufacturer and that medication is dispensed by a licensed third party
- Text support line published with stated hours
- LegitScript certification verified against the issued seal, not just the badge
Watch-outs
- Its own NAD+ product card is labeled CONTAINS TIRZEPATIDE, which contradicts the product it is selling
- No state list is published; the site says only that services are available in most States
- Prices are among the highest in the category, at $349 ongoing for tirzepatide
- Registered at a Sheridan, Wyoming suite address commonly used as a mail-forwarding and registered-agent address
- Terms set arbitration in San Diego under California law while the company address is in Wyoming
- No compounding pharmacy is named
Our Verdict
1st Optimal edges out ClickSlim with a higher overall score of 6.7/10 and is particularly strong for GLP-1 therapy within a lab-driven functional-medicine program. ClickSlim remains a solid alternative, especially if you're looking for the post-introductory price stated up front.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.
Choose ClickSlim if…
You want the post-introductory price stated up front and a starting price around $349/mo.
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Wellorithm
Compounded GLP-1 access with oral tablet options across 49 states
From $147/mo
Get started →Willow
Mainstream telehealth GLP-1 access
From $299/mo
Get started →Sunlight
Compounded GLP-1 with unlimited telehealth visits and free shipping
From $88/mo
Get started →1st Optimal vs ClickSlim: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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