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1st Optimal vs BeyondMD

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
BeyondMD logo

BeyondMD

7.6
★★★3.8/5

Best for: mainstream telehealth GLP-1 access

Visit BeyondMD

1st Optimal and BeyondMD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $139/mo, and BeyondMD edges ahead overall (7.6 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

BeyondMD

StartingCompounded
$139/mo
semaglutide
StartingCompounded
$209/mo
tirzepatide

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What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

BeyondMD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Included

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

BeyondMD

7.6/10

Value25%

6.5A
vs
B
8.5

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
7.3

Accessibility10%

6.5A
vs
B
7.5

Support10%

7.4A
vs
B
7.4

Features & Coverage

Feature1st OptimalBeyondMD
Starting Price$99/mo$139/mo
Features8 features3 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About BeyondMD

Telehealth clinic offering competitively priced compounded semaglutide and tirzepatide.

Read our full BeyondMD review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

BeyondMD

What we like

  • Aggressively low monthly pricing
  • Both semaglutide and tirzepatide available
  • Compounded GLP-1 access

Watch-outs

  • Limited public information on program details

Our Verdict

Winner: BeyondMD

BeyondMD edges out 1st Optimal with a higher overall score of 7.6/10 and is particularly strong for mainstream telehealth GLP-1 access. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose BeyondMD if…

You want mainstream telehealth GLP-1 access and a starting price around $139/mo.

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7.4

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Needle-free, microdosed compounded GLP-1 with lab-monitored care

8.1

GobyMeds

Budget-conscious shoppers

7.6

RNK Health

Compounded GLP-1 alongside NAD+, peptide and longevity add-ons

1st Optimal vs BeyondMD: FAQ

1st Optimal is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $139/mo for BeyondMD. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
BeyondMD scores higher overall at 7.6/10 versus 6.7/10, and is particularly strong for mainstream telehealth GLP-1 access. That said, 1st Optimal is a better fit if you want GLP-1 therapy within a lab-driven functional-medicine program.
Neither 1st Optimal nor BeyondMD publicly lists its exact state availability. Most national GLP-1 telehealth providers operate in the majority of states — confirm your state is covered during sign-up.
Neither 1st Optimal nor BeyondMD is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, 1st Optimal is cheaper at $99/mo versus $139/mo at BeyondMD.

Key terms, explained

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Continue exploring 1st Optimal and BeyondMD head-to-heads in the same category.

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