Naltrexone

Definition

An opioid receptor antagonist used at 50 mg daily for alcohol and opioid use disorder, and at low dose (1.5-4.5 mg, off-label) for various inflammatory conditions. The 8 mg component of Contrave contributes to appetite + reward-pathway modulation when paired with bupropion. Single-agent weight-loss effect is minimal.

GLP-1 vs naltrexone for weight loss →

Definition curated by Weight Loss Rankings — sourced from FDA labels and peer-reviewed PubMed literature, never AI-generated summaries.

Related terms in drug

• Liraglutide
• Exenatide
• Dulaglutide
• Albiglutide
• Contrave
• Qsymia
• Bupropion
• Phentermine
• Topiramate
• Pemvidutide
• Mazdutide

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