Contrave

Definition

An oral fixed-dose combination of naltrexone 8 mg + bupropion 90 mg ER, taken twice daily after a 4-week titration. FDA-approved September 2014 for chronic weight management. Pivotal trial (COR-I) showed -6.1% body weight at 56 weeks. Carries a boxed warning for suicidal behavior in young adults due to the bupropion component.

Contrave drug page →

Definition curated by Weight Loss Rankings — sourced from FDA labels and peer-reviewed PubMed literature, never AI-generated summaries.

Related terms in drug

• Liraglutide
• Exenatide
• Dulaglutide
• Albiglutide
• Qsymia
• Bupropion
• Naltrexone
• Phentermine
• Topiramate
• Pemvidutide
• Mazdutide

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