Exenatide
Definition
A GLP-1 receptor agonist available as twice-daily Byetta and once-weekly Bydureon (extended-release). First GLP-1 approved by the FDA in 2005 for type 2 diabetes. The EXSCEL trial showed neutral CV outcomes — distinguishing exenatide from semaglutide / liraglutide / dulaglutide which all showed CV benefit.
Definition curated by Weight Loss Rankings — sourced from FDA labels and peer-reviewed PubMed literature, never AI-generated summaries.
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