Zappy Health vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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Zappy Health
Best for people wanting both compounded and brand-name GLP-1 with flat pricing that doesn't rise with doseStarting at $159/mo
Amazon One Medical
Best for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savingsStarting at $149/mo
Side-by-Side Comparison
| Feature | Zappy Health | Amazon One Medical |
|---|---|---|
| Overall Score | 6.8/10 | ✓8.7/10 |
| Starting Price | $159/mo | ✓$149/mo |
| Editorial Rating | 3.4 ★ /5 | ✓4.4 ★ /5 |
| Features | ✓8 features | 6 features |
| States Available | 42 | ✓50 |
| Compounded | — | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Zappy Health
What we like
- Both compounded GLP-1 and brand-name Wegovy/Zepbound available
- Flat pricing that doesn't increase as your dose goes up
- Cheaper on longer subscriptions — compounded semaglutide from $159/month
- Online visit with a licensed clinician; no insurance required
Watch-outs
- Third-party reports of an order arriving with an unlicensed-pharmacy label
- Not available in 8 states (HI, AL, AR, CA, KS, MI, MN, MS)
- Operating legal entity isn't clearly disclosed on the site
- Lowest prices require a 9-month commitment
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out Zappy Health with a higher overall score of 8.7/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Zappy Health remains a solid alternative, especially if you're looking for people wanting both compounded and brand-name GLP-1 with flat pricing that doesn't rise with dose.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.