YourHealthRx vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
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YourHealthRx
Best for: Science-forward GLP-1 and peptide care nationwide, with flat-rate dosing and built-in clinical follow-up
Visit YourHealthRx →
Enhance MD
Best for: lab-monitored compounded GLP-1 with mandatory video visit
Visit Enhance MD →YourHealthRx and Enhance MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, YourHealthRx starts lower at $170/mo versus $212/mo, and Enhance MD edges ahead overall (8.6 vs 8.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
YourHealthRx
Weekly injectable + B12; $140 first month and on a 6-month plan. Oral dissolving tablet $180/mo. Flat price regardless of dose.
Weekly injectable + B12; $190 first month and on a 6-month plan. Oral dissolving tablet $220/mo. Flat price regardless of dose.
Enhance MD
What’s included
YourHealthRx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Enhance MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Included
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
YourHealthRx
8.4/10
Enhance MD
8.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | YourHealthRx | Enhance MD |
|---|---|---|
| Starting Price | ✓$170/mo | $212/mo |
| Features | ✓8 features | 6 features |
| States Available | ✓51 | 39 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About YourHealthRx
YourHealthRx is a scientist-founded peptide and GLP-1 telehealth platform available in all 50 states and DC via a multi-state (IMLC) clinician network. Compounded semaglutide and tirzepatide come as a weekly injectable (with B12) or a daily oral tablet, at a flat subscription price that doesn't change with your dose - injectable semaglutide ~$170/mo and tirzepatide ~$210/mo ongoing. It also offers a broad peptide catalog plus lab testing. Prescribing runs through partner clinical workflows; compounded meds aren't FDA-approved, the pharmacy isn't named, and no LegitScript is shown.
Read our full YourHealthRx review →About Enhance MD
Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).
Read our full Enhance MD review →Pros & Cons
YourHealthRx
What we like
- Available in all 50 states and DC through a multi-state (IMLC) licensed clinician network
- Compounded semaglutide and tirzepatide in two formats - weekly injectable (with B12) or daily oral dissolving tablet
- Flat subscription price that doesn't change as your dose increases (no titration penalty)
- Science-forward, clinician-led, with built-in follow-up, lab testing, and a broad peptide and longevity catalog (BPC-157, TB-500, sermorelin, NAD+)
- Transparent, education-first positioning with published medical disclaimer, privacy, and terms
Watch-outs
- Eligibility and prescribing run through partner clinical workflows - YourHealthRx is the platform, not the prescriber or pharmacy
- Compounded medications are not FDA-approved - not brand Wegovy, Ozempic, Zepbound, or Mounjaro
- The compounding pharmacy partner is not named ('transparent sourcing' claimed but no pharmacy disclosed)
- Headline prices include a first-month intro rate; ongoing monthly cost is higher (semaglutide ~$170, tirzepatide ~$210)
- No LegitScript certification displayed
Enhance MD
What we like
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- Unlimited clinician messaging and dose-adjustment support included
Watch-outs
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- No insurance accepted — cash pay, HSA/FSA eligible
- Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out YourHealthRx with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. YourHealthRx remains a solid alternative, especially if you're looking for Science-forward GLP-1 and peptide care nationwide, with flat-rate dosing and built-in clinical follow-up.
Choose YourHealthRx if…
You want Science-forward GLP-1 and peptide care nationwide, with flat-rate dosing and built-in clinical follow-up and a starting price around $170/mo.
Choose Enhance MD if…
You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $212/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online, ranked by our editorial score.
No insurance needed · vetted by our editors
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Get started →YourHealthRx vs Enhance MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.