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Trillium Meds vs Collective

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Trillium Meds logo

Trillium Meds

7.2
★★★3.6/5

Best for: LegitScript-certified compounded GLP-1, all 50 states + PR; sema $119/mo

Visit Trillium Meds
VS
Collective logo

Collective

8.3
★★★★4.2/5

Best for: the lowest flat medication price if you can absorb an annual membership fee

Visit Collective

Trillium Meds and Collective are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Collective starts lower at $59/mo versus $119/mo, and Collective edges ahead overall (8.3 vs 7.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Trillium Meds

3-Month PlanCompounded
$119/mo
semaglutide

Verbatim site meta: 'pricing from $109.' 3-month plan at $119/mo ($357 total); 1-month plan at $159/mo. All-inclusive price covers compounded semaglutide (with B6, dispensed by BPI Labs or ProRx pharmacy), provider consultation, and shipping. No additional fees.

3-Month PlanCompounded
$199/mo
tirzepatide

3-month plan at $199/mo ($599 total); 1-month plan at $249/mo. All-inclusive price covers compounded tirzepatide (with B6, dispensed by BPI Labs or ProRx pharmacy), provider consultation, and shipping. No additional fees.

Collective

Any dose (flat price)Compounded
$59/mo
semaglutide

Verbatim: 'Compounded Semaglutide: $59/month. Same price, every dose. Cancel anytime.' ⛔ EXCLUDES the required membership — the site states 'What does it cost? $59/month + $199 annual membership.' First-year total is $907 ($75.58/mo equivalent).

Any dose (flat price)Compounded
$69/mo
tirzepatide

Verbatim: 'Compounded Tirzepatide: $69/month. Same price, any dose.' ⛔ EXCLUDES the required membership — 'The cost is $69/month + $199 annual membership.' First-year total is $1,027 ($85.58/mo equivalent).

Required annual membership (subscription, medication billed separately)membership subscription
$199/mo

Verbatim: 'Requires Collective membership: 21 day free trial, then a low annual $199 membership fee. No recurring monthly membership charges.' Charged yearly, not monthly. Terms of Use: 'all membership fees are non-refundable, and partial-period refunds are not provided.'

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What’s included

Trillium Meds

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Billed separately

Collective

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Trillium Meds

7.2/10

Overall

Collective

8.3/10

Value25%

7.0A
vs
B
9.4

Effectiveness25%

6.0A
vs
B
8.2

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

7.8A
vs
B
7.2

Accessibility10%

9.5A
vs
B
7.4

Support10%

7.4A
vs
B
8.4

Features & Coverage

FeatureTrillium MedsCollective
Starting Price$119/mo$59/mo
Features8 features3 features
States Available52Not disclosed
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Trillium Meds

Trillium Meds is a small, owner-operated telehealth platform based in Portland, OR that connects patients with independent licensed providers and FDA-registered compounding pharmacies for compounded semaglutide and tirzepatide. Pricing is all-inclusive—covering medication, provider consultation, and shipping—with no membership fees and flexible 1-month, 3-month fixed-dose, or 3-month titrated programs. LegitScript certified and available in all 50 states plus Puerto Rico.

Read our full Trillium Meds review →

About Collective

Collective (collective.org) is a membership-based telehealth platform from the founder of Thrive Market, selling compounded semaglutide and tirzepatide at a flat price on every dose. Medication is billed separately from a required annual membership, and the program bundles unlimited clinician messaging, dietitian access and express cold shipping.

Read our full Collective review →

Pros & Cons

Trillium Meds

What we like

  • LegitScript certified with an active seal; serves all 50 states plus Puerto Rico with no geographic restrictions
  • All-inclusive pricing covers medication, provider consultation, and shipping with no hidden fees or add-ons
  • Two pharmacy options (BPI Labs with B6, ProRx) and three plan structures: 1-month, 3-month fixed, or 3-month titrated
  • Small owner-operated; founder personally handles customer support outside business hours for direct, responsive service
  • Klarna and Affirm financing available; pause anytime with no long-term commitment required

Watch-outs

  • No labs, coaching, or clinical monitoring included — telehealth Rx and pharmacy fulfillment only
  • Small single-operator platform may limit capacity and support consistency as patient volume grows
  • Compounded medications are not FDA-approved; newer platform with limited long-term public track record
  • Tirzepatide from $199/mo (3-mo plan) is mid-market; sema from $119/mo competitive but not lowest available
  • No live video consult disclosed; async intake-form-based provider review by external licensed provider network

Collective

What we like

  • The lowest published compounded GLP-1 medication prices we track — $59/month semaglutide and $69/month tirzepatide
  • Flat pricing at every dose, so titrating up does not raise the bill
  • Unlimited clinician messaging and registered-dietitian access are included rather than upsold
  • 21-day free trial on the membership before the annual fee is charged

Watch-outs

  • The advertised $59 and $69 exclude a mandatory $199 annual membership — the real first-year cost is $907 and $1,027
  • Membership fees are non-refundable and no partial-period refunds are given
  • Compounding pharmacies are described only as 'independent, third-party licensed pharmacies' and are never named
  • State availability is not published on the marketing site

Our Verdict

Winner: Collective

Collective edges out Trillium Meds with a higher overall score of 8.3/10 and is particularly strong for the lowest flat medication price if you can absorb an annual membership fee. Trillium Meds remains a solid alternative, especially if you're looking for LegitScript-certified compounded GLP-1, all 50 states + PR; sema $119/mo.

Choose Trillium Meds if…

You want LegitScript-certified compounded GLP-1, all 50 states + PR; sema $119/mo and a starting price around $119/mo.

Choose Collective if…

You want the lowest flat medication price if you can absorb an annual membership fee and a starting price around $59/mo.

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Trillium Meds vs Collective: FAQ

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