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Shapely vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Shapely logo

Shapely

7.3
★★★3.7/5

Best for: Insurance-accepted telehealth: sema $99/mo, tirz $166/mo; CA/FL/NY/TX

Visit Shapely
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Shapely and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Shapely starts lower at $99/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Shapely

Starter dose (lowest titration)Compounded
$99/mo
semaglutide

Verbatim from semaglutide medication page: 'Starting at $99/month'. Starter 3-month supply at lowest titration dose ($297/quarter). Tiered: ~$139/mo (low-mid dose), ~$179/mo (high dose). Free 2-day shipping; syringes and alcohol pads included. Via state-licensed 503A/503B compounding pharmacy. A separate telehealth recurring plan ($99/mo, $49 first-month promo) is required in addition to the medication cost.

Starter dose (lowest titration)Compounded
$166/mo
tirzepatide

Verbatim from tirzepatide medication page: 'Starting at $166/month'. Starter dose at lowest titration. Tiered: ~$249/mo (low-mid dose), ~$299/mo (high dose). Free 2-day shipping; syringes and alcohol pads included. Via state-licensed 503A/503B compounding pharmacy. Self-pay only for compounded tirz. A separate telehealth recurring plan ($99/mo, $49 first-month promo) is required in addition to the medication cost.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Shapely

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Shapely

7.3/10

Overall

NewSelf

8.3/10

Value25%

7.5A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.3

Accessibility10%

4.5A
vs
B
8.5

Support10%

8.4A
vs
B
7.9

Features & Coverage

FeatureShapelyNewSelf
Starting Price$99/mo$100/mo
Features8 features6 features
States Available449
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNone1 warning

About Shapely

Shapely is a GLP-1 telehealth platform founded by Dr. Justin Zaghi, MD/MBA, a Harvard-trained physician board-certified in both internal medicine and obesity medicine. The service accepts major PPO insurance and Medicare for brand-name GLP-1s including Wegovy, Ozempic, Zepbound, and Mounjaro, while offering compounded semaglutide from $99/month and compounded tirzepatide from $166/month for self-pay patients — both with free 2-day shipping and supplies included via state-licensed 503A/503B pharmacies.

Read our full Shapely review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Shapely

What we like

  • Founded by Dr. Justin Zaghi, MD/MBA — Harvard-trained, board-certified in internal medicine and obesity medicine, with Medical Director Ana Lisa
  • Brand-name GLP-1s (Wegovy, Ozempic, Zepbound, Mounjaro, Foundayo) covered by major PPO and Medicare at copay
  • Compounded semaglutide from $99/month with free 2-day shipping, syringes, and supplies included via 503A/503B pharmacy
  • 1:1 registered dietitian (RDN) and monthly video provider visits included in every plan; unlimited chat and app support
  • Cellular smart scale provided to qualifying patients for ongoing weight tracking throughout the program

Watch-outs

  • Currently available only in California, Florida, New York, and Texas — 46 states unserved despite announced expansion
  • Telehealth subscription ($99/mo self-pay, $49 first-month promo) is charged separately from compounded medication cost
  • Labs not included — $75 flat rate for uninsured patients; baseline bloodwork may be required before prescribing
  • No LegitScript certification found on any public page
  • Compounding pharmacy partner not named publicly; 503A/503B status claimed but specific pharmacy undisclosed

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Shapely with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Shapely remains a solid alternative, especially if you're looking for Insurance-accepted telehealth: sema $99/mo, tirz $166/mo; CA/FL/NY/TX.

Choose Shapely if…

You want Insurance-accepted telehealth: sema $99/mo, tirz $166/mo; CA/FL/NY/TX and a starting price around $99/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Shapely vs NewSelf: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.