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Roen Rx vs Vytora Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Roen Rx logo

Roen Rx

7.1
★★★3.6/5

Best for: patients with insurance seeking brand-name GLP-1 access with compounded fallback

Visit Roen Rx
VS
Vytora Health logo

Vytora Health

8.4
★★★★4.2/5

Best for: compounded or brand-name GLP-1 with named pharmacy partners, 50 states

Visit Vytora Health

Roen Rx and Vytora Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Roen Rx starts lower at $25/mo versus $150/mo, and Vytora Health edges ahead overall (8.4 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Roen Rx

Compounded Semaglutide (3-month supply, medication only)Compounded
$151/mo
semaglutide

Medication price only; a separate Roen Rx membership is required on top.

Compounded Tirzepatide (medication only)Compounded
$216/mo
tirzepatide

Medication price only; membership billed separately.

Brand GLP-1 with insurance (copay)Brand-name
$25/mo
semaglutide

As low as $25 monthly copay with insurance coordination; membership still required.

Required Roen Rx membership (subscription, medication NOT included)membership subscription
$39/mo

First month discounted to $39; standard recurring membership rate not published. GLP-1 medications are not included in the membership fee. drug omitted intentionally.

Semaglutide Bundle (membership + GLP-1, after first month)Compounded
$297/mo
semaglutide

All-in bundle: $217 first month, then $297/mo. 'bundle' in dose keeps it out of the molecule cost-engine so it does not double-count the standalone $151 med row.

Tirzepatide Bundle (membership + GLP-1, after first month)Compounded
$449/mo
tirzepatide

All-in bundle: $349 first month, then $449/mo.

Vytora Health

All dosesCompounded
$180/mo
semaglutide
3-mo bundle ($450 billed)Compounded
$150/mo
semaglutide
All dosesCompounded
$249/mo
tirzepatide
3-mo bundle ($599 billed)Compounded
$200/mo
tirzepatide
Brand 5/7.5/10/12.5/15 mgBrand-name
$1399/mo
mounjaro
Brand 2.5/5/7.5/10/12.5/15 mgBrand-name
$1399/mo
zepbound

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What’s included

Roen Rx

Inclusions not disclosed.

Vytora Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Roen Rx

7.1/10

Overall

Vytora Health

8.4/10

Value25%

7.0A
vs
B
8.0

Effectiveness25%

7.0A
vs
B
8.5

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
9.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

7.4A
vs
B
8.4

Features & Coverage

FeatureRoen RxVytora Health
Starting Price$25/mo$150/mo
Features8 features8 features
States AvailableNot disclosed51
Compounded✓ Yes✓ Yes
Brand Name✓ Yes✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Roen Rx

Roen Rx offers compounded semaglutide as well as brand-name Ozempic, Wegovy, Zepbound, and Mounjaro with insurance coordination. LegitScript approved. Insurance-covered brand GLP-1s as low as $25/mo; compounded semaglutide from $151/mo quarterly.

Read our full Roen Rx review →

About Vytora Health

Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides. It names its pharmacy partners publicly — Vials Pharmacy and Greenwich Biosciences — and discloses its operating physician group, uncommon transparency for the category. Compounded semaglutide runs $180/mo ($150 on a 3-month bundle) and tirzepatide $249/mo ($200 bundled).

Read our full Vytora Health review →

Pros & Cons

Roen Rx

What we like

  • Insurance coordination for brand-name GLP-1s — as low as $25/mo
  • Both compounded and brand-name options
  • LegitScript approved with Compounded USA badge
  • Compounded semaglutide from $151/mo quarterly
  • Also offers primary care, mental health, and other specialties

Watch-outs

  • State availability not publicly disclosed
  • Insurance coordination may not work for all plans
  • Broader platform (ED, hair loss, skincare, birth control)
  • Requires a separate membership (first month $39); GLP-1 medications are NOT included in the membership fee - medication is billed on top

Vytora Health

What we like

  • All 50 states plus DC, with per-state video-vs-audio compliance disclosed
  • Both compounded and brand-name options on one platform — uncommon
  • LegitScript Approved and HIPAA compliant
  • Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
  • Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)
  • Competitive monthly pricing ($180 sema / $249 tirz) plus a 3-month bundle saving 17%
  • Brand-name Mounjaro and Zepbound available at $1,399/mo for FDA-approved options

Watch-outs

  • Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
  • Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
  • Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
  • Initial consultation cost not shown on the public pricing page
  • Limited per-prescriber state licensure detail

Our Verdict

Winner: Vytora Health

Vytora Health edges out Roen Rx with a higher overall score of 8.4/10 and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. Roen Rx remains a solid alternative, especially if you're looking for patients with insurance seeking brand-name GLP-1 access with compounded fallback.

Choose Roen Rx if…

You want patients with insurance seeking brand-name GLP-1 access with compounded fallback and a starting price around $25/mo.

Choose Vytora Health if…

You want compounded or brand-name GLP-1 with named pharmacy partners, 50 states and a starting price around $150/mo.

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7.8

Yucca Health

Mainstream telehealth GLP-1 access

7.7

TrimRx

Best overall value

7.6

Sprout Health

LegitScript-verified compounded GLP-1 via named pharmacies

Roen Rx vs Vytora Health: FAQ

Key terms, explained

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.