RedBox Rx vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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RedBox Rx
Best for: people who want flat-rate compounded glp-1 with either injection or oral dosing
Visit RedBox Rx →
Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →RedBox Rx and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $269/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
RedBox Rx
269/mo month-to-month, or 189/mo on a 6-month plan
daily oral dissolvable tablet
weekly injection, flat pricing
daily oral tablet
Amazon One Medical
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What’s included
RedBox Rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
RedBox Rx
7.8/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | RedBox Rx | Amazon One Medical |
|---|---|---|
| Starting Price | $269/mo | ✓$149/mo |
| Features | 6 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About RedBox Rx
RedBox Rx is a US telehealth pharmacy (parent company Hy-Vee) offering compounded GLP-1 weight management with flat, dose-independent pricing. Compounded semaglutide injection is 269 dollars per month (189 dollars on a 6-month plan) and semaglutide oral tablets are 279 dollars. Compounded tirzepatide injection is 429 dollars per month and oral tirzepatide is 397 dollars. Every plan includes medication, injection supplies, unlimited provider follow-ups by message or video, a metabolic panel and a 30-minute dietitian session. Pricing does not rise with your dose and no insurance is needed.
Read our full RedBox Rx review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
RedBox Rx
What we like
- Flat, dose-independent pricing on both semaglutide and tirzepatide
- Offers both weekly injections and daily oral tablets
- Includes unlimited provider follow-ups, a metabolic panel and a dietitian session
- Backed by grocery-pharmacy parent company Hy-Vee
Watch-outs
- Does not serve every state (for example Mississippi is excluded)
- Does not publicly name its compounding pharmacy
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out RedBox Rx with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. RedBox Rx remains a solid alternative, especially if you're looking for people who want flat-rate compounded glp-1 with either injection or oral dosing.
Choose RedBox Rx if…
You want people who want flat-rate compounded glp-1 with either injection or oral dosing and a starting price around $269/mo.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
Ready to start? Vetted GLP-1 providers
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Get started →Sunlight
Compounded GLP-1 with unlimited telehealth visits and free shipping
From $159/mo
Get started →MadeMed
Compounded GLP-1 in both injection and oral forms
From $219/mo
Get started →RedBox Rx vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.