OrderlyMeds vs Vytora Health
In our scoring, Vytora Health edges ahead overall (8.4 vs 7.8 out of 10), and OrderlyMeds costs less for compounded semaglutide (about $360 a year less).
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Key differences
- Price
- OrderlyMeds $149/mo vs Vytora Health $179/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $360 a year less with OrderlyMeds)
- Coverage
- OrderlyMeds 50 states; Vytora Health 50 states + DC (only Vytora Health: District of Columbia)
- Included
- OrderlyMeds: medication, clinician visits, shipping; Vytora Health: medication, clinician visits, shipping
- Safety
- FDA warning letters on record: OrderlyMeds 1, Vytora Health none
OrderlyMeds
Best for same-price-at-every-dose compounded GLP-1s with no membership fees, plus brand Wegovy and Zepbound
semaglutide
$149
$74 first month
Our score 7.8/10
Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states
semaglutide
$179
Our score 8.4/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
OrderlyMeds
Vytora Health
Price
Semaglutide / month
Better on this row: $149/mo
$74 first month
$179/mo
Semaglutide / year (modeled)
Better on this row: $1,788
$2,148
Tirzepatide / month
$299/mo
$149 first month
Better on this row: $249/mo
Tirzepatide / year (modeled)
$3,588
Better on this row: $2,988
Brand Zepbound / Mounjaro / month
$1,498/mo
Better on this row: $1,399/mo
Brand Zepbound / Mounjaro / year (modeled)
$17,976
Better on this row: $16,788
Brand Wegovy / Ozempic / month
$1,839/mo
Not listed
Coverage
State availability
50 states
50 states + DC
Brand-name access listed
Zepbound / Mounjaro, Wegovy / Ozempic
Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Lab work
Not required
Not disclosed
Cancel anytime
Yes
Yes
Minimum commitment
None; no subscription, charged per refill
None on monthly plans; 3-month plans are billed every 3 months
Refunds
Full refund if you're denied a prescription; no cancellation once the prescription is written
'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'
Early-cancellation fee
None
Not disclosed
FDA warning letters
1 warning letter
Better on this row: None on record
Provider facts checked
October 2026
October 2026
Show where they differ by stateHide state lists
Only Vytora Health (DC)
- District of Columbia
Every dose and plan: OrderlyMeds · Vytora Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose OrderlyMeds if…
- About $360 a year less than Vytora Health for compounded semaglutide at standing prices
- Lists brand-name Wegovy / Ozempic, which Vytora Health doesn't price
- Same price at every dose
What to weigh up
- 1 FDA warning letter on record
- Not available in District of Columbia
Choose Vytora Health if…
- Serves District of Columbia, where OrderlyMeds doesn't
- No FDA warning letters on record (OrderlyMeds has 1)
- Both compounded and brand-name options on one platform
What to weigh up
- About $360 a year more than OrderlyMeds for compounded semaglutide
- Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
OrderlyMeds
7.8/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →From $219/mo
Get started →Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →OrderlyMeds vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.