NewSelf vs PeptidesRx
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →PeptidesRx
Best for: patients prioritizing regulatory compliance in the compounded space
Visit PeptidesRx →NewSelf and PeptidesRx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $169/mo, and NewSelf edges ahead overall (8.3 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
PeptidesRx
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
PeptidesRx
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
PeptidesRx
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | PeptidesRx |
|---|---|---|
| Starting Price | ✓$100/mo | $169/mo |
| Features | 6 features | 6 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About PeptidesRx
PeptidesRx is a Fort Worth, TX-based licensed telehealth platform offering physician-supervised compounded semaglutide, tirzepatide, and a broader prescription peptide menu. Board-certified medical director, licensed nurse practitioners conducting good-faith examinations, transparent pricing, and shipped directly to patients nationwide. Positions itself as a compliance-focused alternative to gray-market peptide vendors.
Read our full PeptidesRx review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
PeptidesRx
What we like
- Compliance-focused positioning vs gray-market vendors
- Board-certified medical director
- Transparent pricing with no surprise fees
- Real prescriptions, not research-chemical channel
Watch-outs
- Smaller scale than Henry Meds or Hims
- Wide peptide menu may distract from GLP-1 focus
Our Verdict
NewSelf edges out PeptidesRx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. PeptidesRx remains a solid alternative, especially if you're looking for patients prioritizing regulatory compliance in the compounded space.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose PeptidesRx if…
You want patients prioritizing regulatory compliance in the compounded space and a starting price around $169/mo.
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DudeMeds
Men seeking no-fee GLP-1 access with oral and injectable options
From $175/mo
Get started →Yucca Health
Mainstream telehealth GLP-1 access
From $146/mo
Get started →TrimRx
Best overall value
From $135/mo
Get started →NewSelf vs PeptidesRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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