Luma Meds vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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Luma Meds
Best for: a LegitScript-certified compounded GLP-1 plan with free shipping
Visit Luma Meds →
Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →Luma Meds and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Luma Meds starts lower at $140/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Luma Meds
Standard monthly rate; $199 first month.
Amortized per-month rate on 3-month plan.
Standard monthly rate; $249 first month.
Amortized per-month rate on 3-month plan.
Amazon One Medical
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What’s included
Luma Meds
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Luma Meds
7.5/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Luma Meds | Amazon One Medical |
|---|---|---|
| Starting Price | ✓$140/mo | $149/mo |
| Features | 6 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Luma Meds
Fully online compounded GLP-1 telehealth offering semaglutide and tirzepatide injections from FDA-regulated 503A and 503B compounding pharmacies. Plans include free discreet shipping, unlimited 24/7 support, and licensed-physician oversight — with no hidden fees. LegitScript certified.
Read our full Luma Meds review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
Luma Meds
What we like
- LegitScript certified — a credibility mark fewer compounded GLP-1 providers carry
- Free discreet shipping and unlimited 24/7 support on every plan
- Compounded semaglutide and tirzepatide from FDA-regulated 503A/503B pharmacies
- '100,000+ members treated' claim with physician-supervised online care
- 3-month bundle pricing brings semaglutide as low as $140/mo
Watch-outs
- Compounding pharmacy partner not publicly named
- States available not published
- Monthly semaglutide ($249/mo) is above many lower-cost compounded competitors
- No oral formulation options listed
- Compounded medications are not FDA-approved
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out Luma Meds with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Luma Meds remains a solid alternative, especially if you're looking for a LegitScript-certified compounded GLP-1 plan with free shipping.
Choose Luma Meds if…
You want a LegitScript-certified compounded GLP-1 plan with free shipping and a starting price around $140/mo.
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
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Get started →Luma Meds vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.