LeanDose vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
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LeanDose
Best for Doctor-supervised compounded semaglutide or tirzepatide with transparent all-inclusive pricingStarting at $159/mo
Enhance MD
Best for lab-monitored compounded GLP-1 with mandatory video visitStarting at $212/mo
Side-by-Side Comparison
| Feature | LeanDose | Enhance MD |
|---|---|---|
| Overall Score | 8.0/10 | ✓8.6/10 |
| Starting Price | ✓$159/mo | $212/mo |
| Editorial Rating | 4 ★ /5 | ✓4.3 ★ /5 |
| Features | ✓8 features | 6 features |
| States Available | 0 | ✓39 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
LeanDose
What we like
- Transparent all-inclusive first-month pricing (compounded semaglutide from $159, tirzepatide from $279)
- Verifiable LegitScript certification (seal ID 49840868) and an FDA-registered compounding pharmacy
- Doctor-prescribed and supervised, with personalized care plans and multi-state clinical support
- Convenient at-home delivery; compounded semaglutide and tirzepatide options
- Honest, modest social proof — 119 five-star patient reviews
Watch-outs
- Compounded medications are not FDA-approved — not brand Wegovy, Ozempic, Zepbound, or Mounjaro
- Headline rates are first-month pricing; your ongoing monthly cost may be higher
- Available in multiple states but the full list is not published on the homepage
- The compounding pharmacy is FDA-registered but not named
Enhance MD
What we like
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- Unlimited clinician messaging and dose-adjustment support included
Watch-outs
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- No insurance accepted — cash pay, HSA/FSA eligible
- Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out LeanDose with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. LeanDose remains a solid alternative, especially if you're looking for Doctor-supervised compounded semaglutide or tirzepatide with transparent all-inclusive pricing.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.