Human+ vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
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Human+
Best for: Cost-conscious shoppers wanting pharmacy-wholesale pricing via a flat membership, in any state
Visit Human+ →
Enhance MD
Best for: lab-monitored compounded GLP-1 with mandatory video visit
Visit Enhance MD →Human+ and Enhance MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Enhance MD starts at $212/mo, and Enhance MD edges ahead overall (8.6 vs 7.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Human+
Pricing not publicly listed.
Enhance MD
What’s included
Human+
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Billed separately
Lab work
Not disclosed
Coaching
Not disclosed
Enhance MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Included
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Human+
7.7/10
Enhance MD
8.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Human+ | Enhance MD |
|---|---|---|
| Starting Price | — | $212/mo |
| Features | ✓8 features | 6 features |
| States Available | ✓50 | 39 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Human+
Human+ (HUMAN+, INC.) is an 'at-cost' telehealth membership in all 50 states: you pay a flat monthly fee and prescriptions are billed at pharmacy-wholesale cost rather than marked up. Weight loss is one of its treatment categories (with hair, sexual wellness, mental health, and labs), filled through US 503A compounding pharmacies and reviewed by board-certified clinicians after a 5-minute intake. Medicine ships in plain packaging. Specific GLP-1 medications and pricing are shown during intake, not published publicly; compounded medications are not FDA-approved.
Read our full Human+ review →About Enhance MD
Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).
Read our full Enhance MD review →Pros & Cons
Human+
What we like
- Cost-transparent model: a flat monthly membership with prescriptions billed at pharmacy-wholesale cost instead of marked up
- Available via telehealth in all 50 states
- Filled by US 503A compounding pharmacies and reviewed by board-certified US-licensed clinicians
- Fast, fully online 5-minute intake with provider review often within hours; discreet plain packaging
- Covers weight loss plus hair, sexual wellness, mental health, and labs under one membership
Watch-outs
- Specific GLP-1 medications and pricing are not published — you only see them after starting the intake
- Compounded medications are not FDA-approved — not brand Wegovy, Ozempic, Zepbound, or Mounjaro
- LegitScript certification is shown only as a self-hosted badge; no verifiable LegitScript seal was found
- Minimal public-facing site and a flat membership fee on top of the medication cost
Enhance MD
What we like
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- Unlimited clinician messaging and dose-adjustment support included
Watch-outs
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- No insurance accepted — cash pay, HSA/FSA eligible
- Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out Human+ with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. Human+ remains a solid alternative, especially if you're looking for Cost-conscious shoppers wanting pharmacy-wholesale pricing via a flat membership, in any state.
Choose Human+ if…
You want Cost-conscious shoppers wanting pharmacy-wholesale pricing via a flat membership, in any state.
Choose Enhance MD if…
You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $212/mo.
Ready to start? Vetted GLP-1 providers
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Needle-free and microdosed compounded GLP-1 options with lab-monitored care
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Oral-lozenge compounded GLP-1 access
From $99/mo
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Shoppers who want low-cost, physician-led compounded GLP-1 with peptide and hormone options
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Get started →Human+ vs Enhance MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.