Harmony Wellness Clinic vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Harmony Wellness Clinic
Best for: Compounded semaglutide and tirzepatide from LegitScript-certified telehealth in 36 states
Visit Harmony Wellness Clinic →
Enhance MD
Best for: lab-monitored compounded GLP-1 with mandatory video visit
Visit Enhance MD →Harmony Wellness Clinic and Enhance MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Harmony Wellness Clinic starts lower at $200/mo versus $212/mo, and Enhance MD edges ahead overall (8.6 vs 6.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Harmony Wellness Clinic
Verbatim from services page: '$200' at Level 1 through '$300' at Level 5. GLP-1 + B12 formulation. Five dose tiers ($200/$225/$250/$275/$300/month); $200 is entry-tier price.
Verbatim from services page: '$250' at Level 1 through '$450' at Level 6. GLP-1/GIP + B12 formulation. Six dose tiers ($250/$300/$350/$400/$450 range); $250 is entry-tier price.
Enhance MD
What’s included
Harmony Wellness Clinic
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Enhance MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Included
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Harmony Wellness Clinic
6.9/10
Enhance MD
8.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Harmony Wellness Clinic | Enhance MD |
|---|---|---|
| Starting Price | ✓$200/mo | $212/mo |
| Features | ✓8 features | 6 features |
| States Available | 36 | ✓39 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Harmony Wellness Clinic
Harmony Wellness Clinic is a LegitScript-certified telehealth platform offering compounded semaglutide (GLP-1 + B12) and compounded tirzepatide (GLP-1/GIP + B12) for medically supervised weight loss. Clinical care is led by Kristina Stout, APRN-CNP, a certified Family Nurse Practitioner with 10 years of healthcare experience. Medications are dispensed through four named 503A compounding pharmacies in Texas and Tennessee and shipped directly to patients. Services are available via the Optimantra online patient portal across 36 states and DC.
Read our full Harmony Wellness Clinic review →About Enhance MD
Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).
Read our full Enhance MD review →Pros & Cons
Harmony Wellness Clinic
What we like
- LegitScript certified with licensed APRN-CNP clinical oversight by Kristina Stout
- Two compounded GLP-1 options: semaglutide+B12 (5 dose levels) and tirzepatide+B12 (6 dose levels)
- Partners with four named 503A compounding pharmacies for a transparent supply chain
- Competitive starting prices: $200/month for semaglutide and $250/month for tirzepatide
- Telehealth services available in 36 states via the Optimantra online patient portal
Watch-outs
- 36-state coverage — many states including some large markets not served
- Care led by APRN-CNP, not an MD or DO; no physician name disclosed
- Pricing scales with dose level up to $300/month (sema) and $450/month (tirz)
- Labs not mentioned or included on any public page — baseline bloodwork protocol unknown
- No coaching or lifestyle program disclosed beyond clinical dose management
Enhance MD
What we like
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- Unlimited clinician messaging and dose-adjustment support included
Watch-outs
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- No insurance accepted — cash pay, HSA/FSA eligible
- Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out Harmony Wellness Clinic with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. Harmony Wellness Clinic remains a solid alternative, especially if you're looking for Compounded semaglutide and tirzepatide from LegitScript-certified telehealth in 36 states.
Choose Harmony Wellness Clinic if…
You want Compounded semaglutide and tirzepatide from LegitScript-certified telehealth in 36 states and a starting price around $200/mo.
Choose Enhance MD if…
You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $212/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online, ranked by our editorial score.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Gala
Compounded GLP-1/GIP combo therapy on a yearly subscription with free shipping nationwide
From $149/mo
Get started →Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $49/mo
Get started →Harmony Wellness Clinic vs Enhance MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Harmony Wellness Clinic and Enhance MD head-to-heads in the same category.
- Harmony Wellness Clinic vs CoreAge Rx
- Harmony Wellness Clinic vs Amazon One Medical
- Harmony Wellness Clinic vs NovoCare Pharmacy
- Enhance MD vs Vytora Health
- Enhance MD vs Noom Med
- Enhance MD vs Novi
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.