Fresh Day Meds vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
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Fresh Day Meds
Best for lowest-cost compounded GLP-1 from a LegitScript-certified Texas platformStarting at $133/mo
Enhance MD
Best for lab-monitored compounded GLP-1 with mandatory video visitStarting at $49/mo
Side-by-Side Comparison
| Feature | Fresh Day Meds | Enhance MD |
|---|---|---|
| Overall Score | 8.2/10 | ✓8.6/10 |
| Starting Price | $133/mo | ✓$49/mo |
| Editorial Rating | 4.1 ★ /5 | ✓4.3 ★ /5 |
| Features | ✓8 features | 6 features |
| States Available | ✓50 | 39 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Fresh Day Meds
Pros
- ✓Among the lowest compounded GLP-1 pricing in the market ($133/mo sema, $166/mo tirz on 3-month bundle)
- ✓LegitScript certified and HIPAA compliant
- ✓Coverage across 49 states plus DC
- ✓Free expedited shipping with prescription review in under 4 hours
- ✓No membership or consultation fees on top of medication price
- ✓Single account covers GLP-1, hair, sexual wellness, TRT, and NAD+/B12
- ✓Houston, TX headquarters publicly disclosed
Cons
- ✗Compounding pharmacy partner not named — only 503A/503B facilities referenced
- ✗Medical director and founder names not disclosed
- ✗Compounded-only — no brand-name fallback if the FDA shortage pathway ends
- ✗State count is inconsistent: ToS lists 49 states + DC (no Arkansas) while About page claims all 50 + DC
- ✗Dose-specific pricing not shown — only flat 'as low as' pricing before checkout
- ✗Medical group operates as Telegra MD LLC (Spokane, WA) — a typical white-label arrangement
Enhance MD
Pros
- ✓Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- ✓Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- ✓Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- ✓Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- ✓Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- ✓Unlimited clinician messaging and dose-adjustment support included
Cons
- ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- ✗Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- ✗Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- ✗No insurance accepted — cash pay, HSA/FSA eligible
- ✗Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out Fresh Day Meds with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. Fresh Day Meds remains a solid alternative, especially if you're looking for lowest-cost compounded GLP-1 from a LegitScript-certified Texas platform.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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