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Enhance MD vs Trimi Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Enhance MD logo

Enhance MD

8.1
★★★★4.1/5

Best for: lab-monitored compounded GLP-1 with mandatory video visit

Visit Enhance MD
VS
Trimi Health logo

Trimi Health

8.3
★★★★4.2/5

Best for: budget-conscious shoppers

Visit Trimi Health

Enhance MD and Trimi Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Trimi Health starts lower at $99/mo versus $212/mo, and Trimi Health edges ahead overall (8.3 vs 8.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Enhance MD

GLP-1 CoreCompounded
$212$112/mo
Save 47% right now
semaglutide
GLP-1 AdvancedCompounded
$280$180/mo
Save 36% right now
tirzepatide
GLP-1 Elite (sema + tirz)Compounded
$322$222/mo
Save 31% right now
tirzepatide

Trimi Health

StartingCompounded
$99/mo
semaglutide
StartingCompounded
$125/mo
tirzepatide

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What’s included

Enhance MD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Included

Coaching

Not disclosed

Trimi Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Enhance MD

8.1/10

Overall

Trimi Health

8.3/10

Value25%

7.0A
vs
B
9.0

Effectiveness25%

9.0A
vs
B
8.0

User Experience15%

8.5A
vs
B
8.0

Trust & Safety15%

8.0A
vs
B
8.5

Accessibility10%

8.0A
vs
B
8.0

Support10%

8.5A
vs
B
8.0

Features & Coverage

FeatureEnhance MDTrimi Health
Starting Price$212/mo$99/mo
Features6 features3 features
States Available3950
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Enhance MD

Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).

Read our full Enhance MD review →

About Trimi Health

Telehealth provider offering some of the lowest compounded GLP-1 pricing available.

Read our full Trimi Health review →

Pros & Cons

Enhance MD

What we like

  • Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
  • Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
  • Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
  • Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
  • Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
  • Unlimited clinician messaging and dose-adjustment support included

Watch-outs

  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
  • Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
  • Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
  • No insurance accepted — cash pay, HSA/FSA eligible
  • Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost

Trimi Health

What we like

  • Aggressively low monthly pricing
  • Both semaglutide and tirzepatide available
  • Compounded GLP-1 access

Watch-outs

  • Limited public information on program details

Our Verdict

Winner: Trimi Health

Trimi Health edges out Enhance MD with a higher overall score of 8.3/10 and is particularly strong for budget-conscious shoppers. Enhance MD remains a solid alternative, especially if you're looking for lab-monitored compounded GLP-1 with mandatory video visit.

Choose Enhance MD if…

You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $212/mo.

Choose Trimi Health if…

You want budget-conscious shoppers and a starting price around $99/mo.

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Enhance MD vs Trimi Health: FAQ

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