DrBrainRx vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
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DrBrainRx
Best for: Neurologist-founded compounded GLP-1 with LegitScript certification and flat-rate pricing
Visit DrBrainRx →
Enhance MD
Best for: lab-monitored compounded GLP-1 with mandatory video visit
Visit Enhance MD →DrBrainRx and Enhance MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, DrBrainRx starts lower at $199/mo versus $212/mo, and Enhance MD edges ahead overall (8.6 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
DrBrainRx
Verbatim from /products/semaglutide: 'The monthly price is the same for all doses and does not increase as your dose goes up.' Includes 4-week vial (0.25–2.5 mg/week range). Plus $25/month provider care fee for dose titration and support (cancellable anytime).
Verbatim from /products/tirzepatide: flat $299 per 4-week vial at all weekly doses (2.5–15 mg). Plus $25/month provider care fee for dose titration and support (cancellable anytime).
Enhance MD
What’s included
DrBrainRx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Enhance MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Included
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
DrBrainRx
7.0/10
Enhance MD
8.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | DrBrainRx | Enhance MD |
|---|---|---|
| Starting Price | ✓$199/mo | $212/mo |
| Features | ✓7 features | 6 features |
| States Available | Not disclosed | 39 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About DrBrainRx
DrBrainRx is a neurologist-founded telehealth clinic led by Dr. Sara Siavoshi (triple board-certified in Neurology, Headache Medicine, and Obesity Medicine) offering compounded semaglutide and tirzepatide injections through USP-certified 503B pharmacies. Flat per-vial monthly pricing covers a 4-week supply at all dose levels, with an additional $25/month provider care fee for dose titration, side-effect management, and clinical messaging. LegitScript certified with 100% online visits and discreet shipping nationwide.
Read our full DrBrainRx review →About Enhance MD
Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).
Read our full Enhance MD review →Pros & Cons
DrBrainRx
What we like
- Founded and overseen by Dr. Sara Siavoshi — triple board-certified in Neurology, Headache Medicine, and Obesity Medicine
- LegitScript certified with compounded medications from USP-certified 503B pharmacies
- Flat-rate pricing — same monthly cost for all dose levels (dose escalation does not raise price)
- 100% online with rapid approvals (~24-48 hours) and discreet shipping in 3–5 business days
- Side-effect support, dose adjustments, and injection guides included with provider care
Watch-outs
- Separate $25/month provider care fee (compounded track) on top of medication cost
- Compounded medications are not FDA-approved individual drugs
- Labs not required or included — no baseline bloodwork protocol disclosed
- States served not published; no explicit list available
- No dedicated coaching program beyond clinical dose management
Enhance MD
What we like
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- Unlimited clinician messaging and dose-adjustment support included
Watch-outs
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- No insurance accepted — cash pay, HSA/FSA eligible
- Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out DrBrainRx with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. DrBrainRx remains a solid alternative, especially if you're looking for Neurologist-founded compounded GLP-1 with LegitScript certification and flat-rate pricing.
Choose DrBrainRx if…
You want Neurologist-founded compounded GLP-1 with LegitScript certification and flat-rate pricing and a starting price around $199/mo.
Choose Enhance MD if…
You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $212/mo.
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Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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