Aspen vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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Aspen
Best for: LegitScript-certified compounded semaglutide/tirzepatide with a named accredited pharmacy and flat dosing
Visit Aspen →
Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →Aspen and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $279/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Aspen
Month-to-month rate (3-month minimum commitment, 3 months shipped upfront, no credit check); drops to $229/mo (3-mo), $209/mo (6-mo) or $179/mo on the 12-month prepay plan.
Aspen's "Most Prescribed" option; month-to-month rate drops to $329/mo (3-mo), $309/mo (6-mo) or $299/mo on the 12-month prepay plan. Same price at every dose.
Amazon One Medical
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What’s included
Aspen
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Aspen
7.6/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Aspen | Amazon One Medical |
|---|---|---|
| Starting Price | $279/mo | ✓$149/mo |
| Features | ✓8 features | 6 features |
| States Available | ✓51 | 50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Aspen
Aspen (Aspen Health Systems LLC) is a LegitScript-certified telehealth clinic offering compounded semaglutide and tirzepatide as physician-chosen weekly injections, with flat pricing at every dose. Semaglutide is $279/mo and tirzepatide $399/mo month-to-month (less on prepay); even the monthly plan requires a 3-month commitment shipped upfront. Prescriptions are filled by Red Rock Compounding Pharmacy (NABP-accredited). Free expedited shipping, no insurance needed, and a money-back guarantee for patients who complete the 28-week program. Available in all 50 states and DC.
Read our full Aspen review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
Aspen
What we like
- LegitScript-certified with an independently verifiable seal (#50306023) and HIPAA compliance — a strong trust signal for a compounded-GLP-1 telehealth
- Names its dispensing pharmacy: Red Rock Compounding Pharmacy, LegitScript-certified and NABP-accredited, licensed in 49 states plus DC
- Flat pricing at every dose ("same price at every dose, no surprises") plus free expedited shipping, so your cost won't rise as you titrate up
- Competitive prepay rates — compounded semaglutide as low as $179/mo (12-mo) and tirzepatide $299/mo — with zero interest and no credit check
- Money-back guarantee for qualifying patients who complete the full 28-week program without losing weight; available in all 50 states + DC
Watch-outs
- Compounded semaglutide and tirzepatide only — no brand-name Wegovy, Zepbound or Ozempic — and compounded GLP-1s aren't FDA-reviewed or approved
- Even the "monthly" plan requires a 3-month commitment with three months of medication shipped and billed upfront — limited month-to-month flexibility
- Standing month-to-month pricing is steep ($279 semaglutide, $399 tirzepatide); the lowest rates require 6- or 12-month prepay
- The provider chooses semaglutide vs tirzepatide for you, so you can't freely pick your own molecule
- Registered as Aspen Health Systems LLC at a Sheridan, WY address; async model with no routine video visit
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out Aspen with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Aspen remains a solid alternative, especially if you're looking for LegitScript-certified compounded semaglutide/tirzepatide with a named accredited pharmacy and flat dosing.
Choose Aspen if…
You want LegitScript-certified compounded semaglutide/tirzepatide with a named accredited pharmacy and flat dosing and a starting price around $279/mo.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
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Breeze Meds
Compounded GLP-1 access with named prescribers and 4-pharmacy network
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Get started →Telos Rx
Needle-free and microdosed compounded GLP-1 options with lab-monitored care
From $49/mo
Get started →GobyMeds
Budget-conscious shoppers
From $93/mo
Get started →Aspen vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.