Alloy vs Signos
An in-depth comparison of two leading GLP-1 Providers
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Alloy
Best for Menopause Society-certified care with the broadest GLP-1 formularyStarting at $80/mo
Signos
Best for Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and appStarting at $199/mo
Side-by-Side Comparison
| Feature | Alloy | Signos |
|---|---|---|
| Overall Score | 7.4/10 | ✓7.5/10 |
| Starting Price | ✓$80/mo | $199/mo |
| Editorial Rating | 3.7 ★ /5 | ✓3.8 ★ /5 |
| Features | 8 features | 8 features |
| States Available | 0 | 0 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
Pros & Cons
Alloy
Pros
- ✓Broadest GLP-1 formulary here: brand Wegovy and Zepbound, oral Wegovy, plus compounded semaglutide, tirzepatide, and liraglutide
- ✓All consulting doctors are certified by The Menopause Society — a rare credential
- ✓Spans the price range: brand Wegovy from $199/mo, compounded liraglutide from $80/mo
- ✓STARTGLP1 promo code takes $50 off the first month
Cons
- ✗Not available in Louisiana or Mississippi
- ✗$49 initial consultation is a non-refundable fee separate from medication cost
- ✗Menopause-focused — best for women in menopause or perimenopause, not men or younger patients
Signos
Pros
- ✓Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- ✓Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- ✓Free rapid shipping; HSA/FSA eligible
- ✓Real-time glucose insights and app coaching to help sustain results after GLP-1
Cons
- ✗Compounded GLP-1s are not FDA-approved finished products
- ✗Headline price is a 6-month-program rate, not month-to-month
- ✗Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- ✗Compounding pharmacy partner and state availability are not published on the landing page
Our Verdict
Signos edges out Alloy with a higher overall score of 7.5/10 and is particularly strong for Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app. Alloy remains a solid alternative, especially if you're looking for Menopause Society-certified care with the broadest GLP-1 formulary.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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