Actin vs Sprout Health
An in-depth comparison of two leading GLP-1 Providers
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Actin
Best for affordable compounded semaglutide with B12 enhancementStarting at $133/mo
Sprout Health
Best for LegitScript-verified compounded GLP-1 via named pharmaciesStarting at $249/mo
Side-by-Side Comparison
| Feature | Actin | Sprout Health |
|---|---|---|
| Overall Score | 7.0/10 | ✓7.5/10 |
| Starting Price | ✓$133/mo | $249/mo |
| Editorial Rating | 3.5 ★ /5 | ✓3.8 ★ /5 |
| Features | 2 features | ✓4 features |
| States Available | 0 | ✓44 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Actin
Pros
- ✓Semaglutide + B12 combination for added energy support
- ✓Transparent pricing — exact cost shown upfront with no hidden fees
- ✓Competitive starting price from $133
Cons
- ✗Semaglutide only — no tirzepatide or liraglutide
- ✗No visible LegitScript or PCAB accreditation
- ✗State availability not disclosed
- ✗Broader platform (hormones, sexual wellness, hair health)
Sprout Health
Pros
- ✓LegitScript certification confirmed
- ✓Both compounded semaglutide and tirzepatide available
- ✓44-state coverage via a pre-qualification quiz and licensed clinician review
- ✓Two named 503A pharmacy partners: Foothills Pharmacy and Promise Pharmacy
Cons
- ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- ✗Not available in Alabama, Arkansas, California, Louisiana, Mississippi, or North Dakota
- ✗Relatively high base pricing ($249/mo for sema, $299/mo for tirz) compared to intro-priced competitors
- ✗Pharmacy partner accreditation details (PCAB/ACHC) not independently verified
Our Verdict
Sprout Health edges out Actin with a higher overall score of 7.5/10 and is particularly strong for LegitScript-verified compounded GLP-1 via named pharmacies. Actin remains a solid alternative, especially if you're looking for affordable compounded semaglutide with B12 enhancement.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.