Actin vs SkinnyRx
An in-depth comparison of two leading GLP-1 Providers
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Actin
Best for affordable compounded semaglutide with B12 enhancementStarting at $133/mo
SkinnyRx
Best for mainstream telehealth GLP-1 accessStarting at $199/mo
Side-by-Side Comparison
| Feature | Actin | SkinnyRx |
|---|---|---|
| Overall Score | 7.0/10 | ✓7.4/10 |
| Starting Price | ✓$133/mo | $199/mo |
| Editorial Rating | 3.5 ★ /5 | ✓3.7 ★ /5 |
| Features | 2 features | ✓3 features |
| States Available | 0 | 0 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | ✓None | 1 warning |
Pros & Cons
Actin
Pros
- ✓Semaglutide + B12 combination for added energy support
- ✓Transparent pricing — exact cost shown upfront with no hidden fees
- ✓Competitive starting price from $133
Cons
- ✗Semaglutide only — no tirzepatide or liraglutide
- ✗No visible LegitScript or PCAB accreditation
- ✗State availability not disclosed
- ✗Broader platform (hormones, sexual wellness, hair health)
SkinnyRx
Pros
- ✓Both semaglutide and tirzepatide available
- ✓Compounded GLP-1 access
- ✓Tiered monthly pricing starting at $199/month
- ✓Licensed US clinicians on every prescription
- ✓Discreet shipping included; cancel anytime
Cons
- ✗Limited public information on program details
- ✗States_available not publicly disclosed — gated behind signup intake
Our Verdict
SkinnyRx edges out Actin with a higher overall score of 7.4/10 and is particularly strong for mainstream telehealth GLP-1 access. Actin remains a solid alternative, especially if you're looking for affordable compounded semaglutide with B12 enhancement.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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