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Actin vs OnlyRx

An in-depth comparison of two leading GLP-1 Providers

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7.0

Actin

Best for affordable compounded semaglutide with B12 enhancement
★★★★☆3.5

Starting at $133/mo

Compounded SemaglutideB12 Enhanced
Visit Actin →
6.4

OnlyRx

Best for Buyers comparing cash-pay compounded-GLP-1 platforms who want oral-tablet form factors (ODT) alongside the standard subcutaneous injection, value the transparency of named prescribers + named pharmacy partners, and accept a four-pharmacy fulfillment model rather than a single named compounder.
★★★☆☆3.2

Starting at $179/mo

Compounded Semaglutide (injection + ODT)Compounded Tirzepatide (injection + ODT)Branded Ozempic/Wegovy/Zepbound/Mounjaro Available4 Named Physicians (MD/DO)
Visit OnlyRx →

Side-by-Side Comparison

FeatureActinOnlyRx
Overall Score✓7.0/106.4/10
Starting Price✓$133/mo$179/mo
Editorial Rating✓3.5 ★ /53.2 ★ /5
Features2 features✓10 features
States Available00
Compounded✓ Yes—
Brand Name——
FSA/HSA Accepted——
FDA WarningsNoneNone

Pros & Cons

Actin

Pros

  • ✓Semaglutide + B12 combination for added energy support
  • ✓Transparent pricing — exact cost shown upfront with no hidden fees
  • ✓Competitive starting price from $133

Cons

  • ✗Semaglutide only — no tirzepatide or liraglutide
  • ✗No visible LegitScript or PCAB accreditation
  • ✗State availability not disclosed
  • ✗Broader platform (hormones, sexual wellness, hair health)

OnlyRx

Pros

  • ✓Four-pharmacy fulfillment network (Belmar, Strive, Epiq Scripts, Casa Pharma RX) — three of four are already in our pharmacy registry with independent verification
  • ✓Named prescriber roster on the public site (Dr. Carr MD, Dr. Tenbrink MD, Dr. Italia MD, Dr. Mansour DO) — stronger transparency than peers with anonymous clinical networks
  • ✓ODT (oral disintegrating tablet) compounded form for both semaglutide and tirzepatide — uncommon offering that fits needle-averse patients
  • ✓Server-side rendered Nuxt site (not a SPA blank shell) — pricing, drug list, pharmacy partners, and physician roster all extractable from the static HTML, reducing the YMYL opacity penalty most newer entrants take
  • ✓LegitScript Certified claim on the public site
  • ✓Branded Ozempic/Wegovy/Zepbound/Mounjaro available alongside the compounded line — patients can step up to FDA-approved branded products without switching platforms

Cons

  • ✗Promo pricing ($179 semaglutide injection floor) is marketed prominently; the post-promo maintenance dose pricing is not surfaced on the static site
  • ✗No specific titration ladder pricing — buyers can't see what they'll pay at 1.0 mg or 2.4 mg semaglutide maintenance
  • ✗Refund / cancellation policy not stated on the homepage
  • ✗Lab-work requirement not stated — most legitimate GLP-1 telehealth platforms require baseline labs or a recent metabolic panel
  • ✗LegitScript merchant-ID independent lookup at safe.legitscript.com NOT verified this cycle (claim is on the site but independent confirmation pending)
  • ✗Operating corporate entity not disclosed in the static HTML — the platform self-describes as connecting patients to independent licensed providers but does not name the operating LLC or corporation
  • ✗Epiq Scripts is the one named pharmacy partner not yet independently verified in our pharmacy registry

Our Verdict

Winner: ActinScore: 7.0/10

Actin edges out OnlyRx with a higher overall score of 7.0/10 and is particularly strong for affordable compounded semaglutide with B12 enhancement. OnlyRx remains a solid alternative, especially if you're looking for Buyers comparing cash-pay compounded-GLP-1 platforms who want oral-tablet form factors (ODT) alongside the standard subcutaneous injection, value the transparency of named prescribers + named pharmacy partners, and accept a four-pharmacy fulfillment model rather than a single named compounder..

Get Started with Actin →Get Started with OnlyRx →

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.