Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

Actin vs FMmeds

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

7.0

Actin

Best for affordable compounded semaglutide with B12 enhancement
★★★★☆3.5

Starting at $133/mo

Compounded SemaglutideB12 Enhanced
Visit Actin →
7.9

FMmeds

Best for Cost-conscious patients seeking compounded GLP-1 therapy on a longer commitment tier (12-month semaglutide at $95/mo is near the bottom of the WLR compounded cluster)Patients who prefer flat per-dose pricing and want to escalate dose without per-tier markupsPatients switching from another DTC compounded provider who want to retain their prior dose level (2-week clinician window)Patients in all 50 states + DC who want a free initial telehealth visit before financial commitment
★★★★☆4

Starting at $/mo

Compounded semaglutide + Vitamin B12 co-formulationCompounded tirzepatide + Vitamin B12 co-formulationFlat pricing across all dose strengths (no dose-tier markups)Four commitment tiers (Monthly / 3-Month / 6-Month / 12-Month)
Visit FMmeds →

Side-by-Side Comparison

FeatureActinFMmeds
Overall Score7.0/10✓7.9/10
Starting Price$133/mo$/mo
Editorial Rating3.5 ★ /5✓4 ★ /5
Features2 features✓12 features
States Available0✓51
Compounded✓ Yes—
Brand Name——
FSA/HSA Accepted——
FDA Warnings✓None4 warnings

Pros & Cons

Actin

Pros

  • ✓Semaglutide + B12 combination for added energy support
  • ✓Transparent pricing — exact cost shown upfront with no hidden fees
  • ✓Competitive starting price from $133

Cons

  • ✗Semaglutide only — no tirzepatide or liraglutide
  • ✗No visible LegitScript or PCAB accreditation
  • ✗State availability not disclosed
  • ✗Broader platform (hormones, sexual wellness, hair health)

FMmeds

Pros

  • ✓All 50 states + DC service area enumerated verbatim in Terms
  • ✓Operating LLC and full Manhattan Beach CA address disclosed in Terms / Privacy / Arbitration opt-out
  • ✓Named 503A pharmacy partner (Manifest Pharmacy, Greer SC) — same partner used by Obu Health and VitaraRx in the WLR directory
  • ✓Aggressive 12-month pricing — semaglutide $95/mo and tirzepatide $145/mo on the 12-month tier are at the low end of the WLR compounded-GLP-1 cluster
  • ✓Flat pricing across all dose strengths — no dose-escalation surcharge
  • ✓Free initial telehealth visit (only billed on prescription approval)
  • ✓Free express shipping included in every tier
  • ✓Switcher-friendly: clinician may approve a starting dose matching the patient's prior prescription within a 2-week window

Cons

  • ✗Compounded medications only — no FDA-approved Wegovy / Ozempic / Mounjaro / Zepbound
  • ✗Verbatim FDA-compounded disclaimer published: 'This is a compounded medication. It is not FDA-approved'
  • ✗Clinical network not separately named (unlike Coby / BraveRx / AVARA which disclose Beluga Health)
  • ✗Specific LegitScript ID was not extracted from the SPA bundle — only the 'LegitScript Certified' string and badge asset are visible; ID flagged for next 90-day re-check
  • ✗No PCAB accreditation explicitly claimed in the bundled site copy
  • ✗No BBB profile found for FMmeds or Med Excellence United LLC on bbb.org search 2026-05-29
  • ✗14-day right-to-withdraw but shipped prescription medications are non-returnable (standard for the category)
  • ✗Refund timeline 7-10 business days once approved

Our Verdict

Winner: FMmedsScore: 7.9/10

FMmeds edges out Actin with a higher overall score of 7.9/10 and is particularly strong for Cost-conscious patients seeking compounded GLP-1 therapy on a longer commitment tier (12-month semaglutide at $95/mo is near the bottom of the WLR compounded cluster),Patients who prefer flat per-dose pricing and want to escalate dose without per-tier markups,Patients switching from another DTC compounded provider who want to retain their prior dose level (2-week clinician window),Patients in all 50 states + DC who want a free initial telehealth visit before financial commitment. Actin remains a solid alternative, especially if you're looking for affordable compounded semaglutide with B12 enhancement.

Get Started with Actin →Get Started with FMmeds →

Glossary references

Key terms in this article, linked to their canonical definitions.

Related comparisons

Continue exploring Actin and FMmeds head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.