9amHealth vs Signos
An in-depth comparison of two leading GLP-1 Providers
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9amHealth
Best for Insured patients wanting branded GLP-1s within a full cardiometabolic care programStarting at $149/mo
Signos
Best for Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and appStarting at $199/mo
Side-by-Side Comparison
| Feature | 9amHealth | Signos |
|---|---|---|
| Overall Score | ✓7.6/10 | 7.5/10 |
| Starting Price | ✓$149/mo | $199/mo |
| Editorial Rating | 3.8 ★ /5 | 3.8 ★ /5 |
| Features | 7 features | ✓8 features |
| States Available | 0 | 0 |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
Pros & Cons
9amHealth
Pros
- ✓Prescribes FDA-approved branded GLP-1s (Wegovy, Zepbound, Saxenda)
- ✓$149/month membership or free when covered by insurance
- ✓Membership includes specialists, labs, devices, and medications
- ✓Board-certified obesity specialists (DABOM), endocrinologists, dietitians, PharmDs
- ✓Helps navigate insurance approvals; employer and state-plan partnerships
- ✓Home lab draws available in some areas
- ✓Cardiometabolic whole-body care beyond weight loss
Cons
- ✗Medication coverage and GLP-1 access depend on insurance and BMI criteria
- ✗State availability not enumerated on the public site
- ✗Branded GLP-1s can be costly without insurance coverage
- ✗Pricing for medications not transparently listed
Signos
Pros
- ✓Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- ✓Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- ✓Free rapid shipping; HSA/FSA eligible
- ✓Real-time glucose insights and app coaching to help sustain results after GLP-1
Cons
- ✗Compounded GLP-1s are not FDA-approved finished products
- ✗Headline price is a 6-month-program rate, not month-to-month
- ✗Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- ✗Compounding pharmacy partner and state availability are not published on the landing page
Our Verdict
9amHealth edges out Signos with a higher overall score of 7.6/10 and is particularly strong for Insured patients wanting branded GLP-1s within a full cardiometabolic care program. Signos remains a solid alternative, especially if you're looking for Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.