24hrDOC vs Jyra Health
An in-depth comparison of two leading GLP-1 Providers
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24hrDOC
Best for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatideStarting at $149/mo
Jyra Health
Best for Budget shoppers wanting very low-cost compounded semaglutide or tirzepatide in any stateStarting at $133/mo
Side-by-Side Comparison
| Feature | 24hrDOC | Jyra Health |
|---|---|---|
| Overall Score | 7.1/10 | ✓7.6/10 |
| Starting Price | $149/mo | ✓$133/mo |
| Editorial Rating | 3.6 ★ /5 | ✓3.8 ★ /5 |
| Features | 8 features | 8 features |
| States Available | 0 | ✓50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
24hrDOC
What we like
- Low compounded semaglutide price, around 149 per month
- Fast model: 10-minute assessment, Rx within 45 minutes
- Injectable and oral semaglutide plus tirzepatide options
- 24/7 availability with unlimited provider messaging
Watch-outs
- Compounded only, not FDA-approved branded GLP-1s
- Self-pay only, no insurance accepted
- States served not disclosed on the site
- Fast-prescribing model offers less in-depth clinical workup
Jyra Health
What we like
- Among the lowest compounded pricing — semaglutide from $99/mo and tirzepatide from $133/mo, with no membership and no hidden fees
- Board-certified providers in all 50 states; no insurance required and free express delivery
- Offers both compounded semaglutide and tirzepatide, plus a longevity track
- Full legal suite published (Privacy, Terms, HIPAA, Refunds & Cancellations)
Watch-outs
- The $133/mo tirzepatide price is flagged 'limited time' — verify current pricing before enrolling
- Compounded medications are not FDA-approved (the site discloses this) — not brand Wegovy, Zepbound, Ozempic, or Mounjaro
- Displays a self-hosted LegitScript badge but no verifiable seal or listing
- Compounding pharmacy not named; appears to be a newer, smaller clinic (~300 patients/month)
Our Verdict
Jyra Health edges out 24hrDOC with a higher overall score of 7.6/10 and is particularly strong for Budget shoppers wanting very low-cost compounded semaglutide or tirzepatide in any state. 24hrDOC remains a solid alternative, especially if you're looking for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.