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24hrDOC vs Cost Plus Drugs

An in-depth comparison of two leading GLP-1 Providers

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7.1

24hrDOC

Best for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide
★★★3.6

Starting at $149/mo

Compounded semaglutideOral semaglutide tabletsTirzepatide option$149/mo starting price
Visit 24hrDOC
8.5

Cost Plus Drugs

Best for the cheapest transparent-pricing brand-name Ozempic channel
★★★★4.3

Starting at $279/mo

BrandOzempicAll 50 StatesInsurance Coordination
Visit Cost Plus Drugs

Side-by-Side Comparison

Feature24hrDOCCost Plus Drugs
Overall Score7.1/108.5/10
Starting Price$149/mo$279/mo
Editorial Rating3.6 ★ /54.3 ★ /5
Features8 features5 features
States Available050
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

Pros & Cons

24hrDOC

Pros

  • Low compounded semaglutide price, around 149 per month
  • Fast model: 10-minute assessment, Rx within 45 minutes
  • Injectable and oral semaglutide plus tirzepatide options
  • 24/7 availability with unlimited provider messaging

Cons

  • Compounded only, not FDA-approved branded GLP-1s
  • Self-pay only, no insurance accepted
  • States served not disclosed on the site
  • Fast-prescribing model offers less in-depth clinical workup

Cost Plus Drugs

Pros

  • Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
  • Around $279/mo for branded Ozempic — well below typical retail list prices
  • Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
  • Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
  • Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing

Cons

  • Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
  • Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
  • Wegovy availability has been spotty — check current stock before assuming it ships
  • No compounded semaglutide or tirzepatide — brand only
  • No clinical follow-up — side-effect monitoring falls to your prescribing clinician

Our Verdict

Winner: Cost Plus DrugsScore: 8.5/10

Cost Plus Drugs edges out 24hrDOC with a higher overall score of 8.5/10 and is particularly strong for the cheapest transparent-pricing brand-name Ozempic channel. 24hrDOC remains a solid alternative, especially if you're looking for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide.

Glossary references

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.