Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

24hrDOC vs CLYR Health

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
24hrDOC logo

24hrDOC

7.1
★★★3.6/5

Best for: Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide

Visit 24hrDOC
VS
CLYR Health logo

CLYR Health

7.7
★★★3.9/5

Best for: Flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up

Visit CLYR Health

24hrDOC and CLYR Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 24hrDOC starts lower at $149/mo versus $229/mo, and CLYR Health edges ahead overall (7.7 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

24hrDOC

0.25-2 mg titrated, once weeklyCompounded
$149/mo
semaglutide
Oral semaglutide tabletsCompounded
$309/mo
semaglutide
StartingCompounded
$239/mo
tirzepatide

Tirzepatide $239/mo sale (regular $339/mo); semaglutide $149/mo

CLYR Health

Compounded semaglutide + B12Compounded
$229/mo
semaglutide

Flat any-dose $229/mo; 3-month prepay $189/mo ($567 billed once)

Compounded tirzepatide + B12Compounded
$249/mo
tirzepatide

$249/mo standard dose (up to 3mL); 3-month prepay $199/mo; higher dose 4-8mL $349/mo

Get alerted when GLP-1 prices drop

Join the GLP-1 price-watch list — we re-verify 360+ providers' prices on their own sites and email you when tracked prices move.

What’s included

24hrDOC

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

CLYR Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

24hrDOC

7.1/10

Overall

CLYR Health

7.7/10

Value25%

7.5A
vs
B
7.5

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

6.8A
vs
B
8.0

Accessibility10%

7.0A
vs
B
7.0

Support10%

7.4A
vs
B
7.0

Features & Coverage

Feature24hrDOCCLYR Health
Starting Price$149/mo$229/mo
Features8 features6 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 24hrDOC

24hrDOC is a fast cash-pay telehealth service that prescribes compounded GLP-1 medications for weight loss, including once-weekly semaglutide injections, oral semaglutide tablets, and tirzepatide. Compounded semaglutide runs about 149 dollars per month (from 249), with a 100 dollar first-order discount and doses titrated from 0.25 mg to 2 mg. The model emphasizes speed: a roughly 10-minute assessment, prescriptions within about 45 minutes, unlimited messaging, and discreet shipping from licensed pharmacies. Self-pay only, no insurance, operating 24/7. States served are not listed online.

Read our full 24hrDOC review →

About CLYR Health

CLYR Health is a Florida-based telehealth pharmacy offering compounded GLP-1 weight-loss injections alongside sexual-health, longevity and wellness treatments. It sells compounded semaglutide + B12 from $229/mo and compounded tirzepatide + B12 from $249/mo on flat 'any dose, one price' billing, with 3-month prepay plans that lower the effective rate. Brand Zepbound and oral GLP-1 options are also listed. LegitScript Certified and fulfilled by a named 503A pharmacy.

Read our full CLYR Health review →

Pros & Cons

24hrDOC

What we like

  • Low compounded semaglutide price, around 149 per month
  • Fast model: 10-minute assessment, Rx within 45 minutes
  • Injectable and oral semaglutide plus tirzepatide options
  • 24/7 availability with unlimited provider messaging

Watch-outs

  • Compounded only, not FDA-approved branded GLP-1s
  • Self-pay only, no insurance accepted
  • States served not disclosed on the site
  • Fast-prescribing model offers less in-depth clinical workup

CLYR Health

What we like

  • Flat 'any dose, one price' billing so the monthly cost does not rise as your dose climbs
  • LegitScript Certified with a named 503A pharmacy partner (The Pharmacy Hub, Miami FL) and MD Integrations clinicians
  • 3-month prepay drops semaglutide to $189/mo and tirzepatide to $199/mo

Watch-outs

  • State availability gated behind intake; not published on the marketing site
  • Standing monthly rates ($229-249) run above the cheapest compounded competitors
  • Broad catalog (weight loss, sexual health, longevity) rather than a weight-loss specialist

Our Verdict

Winner: CLYR Health

CLYR Health edges out 24hrDOC with a higher overall score of 7.7/10 and is particularly strong for Flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up. 24hrDOC remains a solid alternative, especially if you're looking for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide.

Choose 24hrDOC if…

You want Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide and a starting price around $149/mo.

Choose CLYR Health if…

You want Flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up and a starting price around $229/mo.

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online.

No insurance needed · vetted by our editors

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

8.1

Oak

Compounded semaglutide and tirzepatide at a flat monthly price

7.1

Bodybuilding Health+

Fitness-brand compounded GLP-1 with hormone and performance programs

7.4

Brightmeds

Compounded or brand GLP-1 bundled with TRT and peptides for men

24hrDOC vs CLYR Health: FAQ

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring 24hrDOC and CLYR Health head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.