24hrDOC vs AlyveRx
An in-depth comparison of two leading GLP-1 Providers
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24hrDOC
Best for: Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide
Visit 24hrDOC →AlyveRx
Best for: people who want needle-free sublingual GLP-1 options alongside standard compounded injections
Visit AlyveRx →24hrDOC and AlyveRx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 24hrDOC starts lower at $149/mo versus $183/mo, and 24hrDOC edges ahead overall (7.1 vs 6.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
24hrDOC
Tirzepatide $239/mo sale (regular $339/mo); semaglutide $149/mo
AlyveRx
Compounded injection, from 183/mo; billed monthly, lower on longer plans
Compounded injection, standing month-to-month price; from 283/mo on multi-month plans
Needle-free sublingual drops, from 203/mo
Needle-free sublingual drops, from 249/mo
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What’s included
24hrDOC
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
AlyveRx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
24hrDOC
7.1/10
AlyveRx
6.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 24hrDOC | AlyveRx |
|---|---|---|
| Starting Price | ✓$149/mo | $183/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 24hrDOC
24hrDOC is a fast cash-pay telehealth service that prescribes compounded GLP-1 medications for weight loss, including once-weekly semaglutide injections, oral semaglutide tablets, and tirzepatide. Compounded semaglutide runs about 149 dollars per month (from 249), with a 100 dollar first-order discount and doses titrated from 0.25 mg to 2 mg. The model emphasizes speed: a roughly 10-minute assessment, prescriptions within about 45 minutes, unlimited messaging, and discreet shipping from licensed pharmacies. Self-pay only, no insurance, operating 24/7. States served are not listed online.
Read our full 24hrDOC review →About AlyveRx
AlyveRx (Alyve, Inc.) is a US online telehealth platform connecting patients with licensed providers for GLP-1 weight loss care, no insurance required, with free discreet delivery. It offers compounded semaglutide and tirzepatide as injections and as needle-free sublingual drops using its proprietary PermeAct delivery tech, and also carries brand Ozempic, Wegovy, and Mounjaro. Month-to-month pricing starts near 183 dollars for compounded semaglutide and 329 dollars for compounded tirzepatide, with lower rates on longer plans. Care is fully online after a telehealth assessment.
Read our full AlyveRx review →Pros & Cons
24hrDOC
What we like
- Low compounded semaglutide price, around 149 per month
- Fast model: 10-minute assessment, Rx within 45 minutes
- Injectable and oral semaglutide plus tirzepatide options
- 24/7 availability with unlimited provider messaging
Watch-outs
- Compounded only, not FDA-approved branded GLP-1s
- Self-pay only, no insurance accepted
- States served not disclosed on the site
- Fast-prescribing model offers less in-depth clinical workup
AlyveRx
What we like
- Offers compounded semaglutide and tirzepatide as both injections and needle-free sublingual drops for people who dislike needles
- Transparent monthly pricing shown upfront, no insurance required, and free discreet delivery
- Also carries brand-name Ozempic, Wegovy, and Mounjaro through its provider network
Watch-outs
- Does not publicly name its dispensing pharmacy or display a LegitScript seal, so third-party accreditation is unverified
- Sublingual GLP-1 absorption relies on the company proprietary PermeAct technology and is not FDA-reviewed for weight loss
- State availability is not published on the site
Our Verdict
24hrDOC edges out AlyveRx with a higher overall score of 7.1/10 and is particularly strong for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide. AlyveRx remains a solid alternative, especially if you're looking for people who want needle-free sublingual GLP-1 options alongside standard compounded injections.
Choose 24hrDOC if…
You want Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide and a starting price around $149/mo.
Choose AlyveRx if…
You want people who want needle-free sublingual GLP-1 options alongside standard compounded injections and a starting price around $183/mo.
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Found
Mainstream telehealth GLP-1 access
From $99/mo
Get started →Breeze Meds
Compounded GLP-1 access with named prescribers and 4-pharmacy network
From $169/mo
Get started →Telos Rx
Needle-free and microdosed compounded GLP-1 options with lab-monitored care
From $49/mo
Get started →24hrDOC vs AlyveRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.