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24hrDOC vs Actin

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
24hrDOC logo

24hrDOC

7.1
★★★3.6/5

Best for: Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide

Visit 24hrDOC
VS
Actin logo

Actin

7.0
★★★3.5/5

Best for: affordable compounded semaglutide with B12 enhancement

Visit Actin

24hrDOC and Actin are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 24hrDOC starts lower at $149/mo versus $169/mo, and 24hrDOC edges ahead overall (7.1 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

24hrDOC

0.25-2 mg titrated, once weeklyCompounded
$149/mo
semaglutide
Oral semaglutide tabletsCompounded
$309/mo
semaglutide
StartingCompounded
$239/mo
tirzepatide

Tirzepatide $239/mo sale (regular $339/mo); semaglutide $149/mo

Actin

Compounded GLP-1 (semaglutide + B12)Compounded
$169/mo
semaglutide

month-to-month; $143/mo on the 3-month plan, $116/mo on the 6-month plan

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What’s included

24hrDOC

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Actin

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

24hrDOC

7.1/10

Overall

Actin

7.0/10

Value25%

7.5A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

7.0A
vs
B
7.0

Trust & Safety15%

6.8A
vs
B
7.3

Accessibility10%

7.0A
vs
B
7.0

Support10%

7.4A
vs
B
7.0

Features & Coverage

Feature24hrDOCActin
Starting Price$149/mo$169/mo
Features8 features3 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 24hrDOC

24hrDOC is a fast cash-pay telehealth service that prescribes compounded GLP-1 medications for weight loss, including once-weekly semaglutide injections, oral semaglutide tablets, and tirzepatide. Compounded semaglutide runs about 149 dollars per month (from 249), with a 100 dollar first-order discount and doses titrated from 0.25 mg to 2 mg. The model emphasizes speed: a roughly 10-minute assessment, prescriptions within about 45 minutes, unlimited messaging, and discreet shipping from licensed pharmacies. Self-pay only, no insurance, operating 24/7. States served are not listed online.

Read our full 24hrDOC review →

About Actin

Actin offers compounded semaglutide with B12 for weight loss. Also provides hormone, sexual wellness, and hair health treatments. Transparent pricing starting from $133.

Read our full Actin review →

Pros & Cons

24hrDOC

What we like

  • Low compounded semaglutide price, around 149 per month
  • Fast model: 10-minute assessment, Rx within 45 minutes
  • Injectable and oral semaglutide plus tirzepatide options
  • 24/7 availability with unlimited provider messaging

Watch-outs

  • Compounded only, not FDA-approved branded GLP-1s
  • Self-pay only, no insurance accepted
  • States served not disclosed on the site
  • Fast-prescribing model offers less in-depth clinical workup

Actin

What we like

  • Semaglutide paired with B12 for added energy support
  • Transparent pricing — exact cost shown upfront with no hidden fees
  • Competitive pricing from $116/mo on the 6-month plan ($169/mo month-to-month)

Watch-outs

  • Semaglutide only — no tirzepatide or liraglutide
  • No visible LegitScript or PCAB accreditation
  • States served not disclosed
  • Broad platform spanning hormones, sexual wellness, and hair health

Our Verdict

Winner: 24hrDOC

24hrDOC edges out Actin with a higher overall score of 7.1/10 and is particularly strong for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide. Actin remains a solid alternative, especially if you're looking for affordable compounded semaglutide with B12 enhancement.

Choose 24hrDOC if…

You want Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide and a starting price around $149/mo.

Choose Actin if…

You want affordable compounded semaglutide with B12 enhancement and a starting price around $169/mo.

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24hrDOC vs Actin: FAQ

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