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1st Optimal vs Try Ageless

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Try Ageless logo

Try Ageless

6.9
★★★3.5/5

Best for: lowest-tier compounded GLP-1 in injection, troche and sublingual forms

Visit Try Ageless

1st Optimal and Try Ageless are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Try Ageless starts at $119/mo, and Try Ageless edges ahead overall (6.9 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Pricing not publicly listed.

Try Ageless

Injection (lowest dose, shop price)Compounded
$119/mo
semaglutide

Shop standing price $119-$229/mo by dose (0.25-2.5 mg); $50-off intro coupon GLP150. A separate plan-based funnel prices sema injection at $279/mo month-to-month down to $199/mo on annual commitment.

Injection (lowest dose, shop price)Compounded
$169/mo
tirzepatide

Shop category standing price (was $219). Plan-based funnel: $349/mo month-to-month down to $249/mo annual.

Drops / sublingual (lowest dose)Compounded · oral
$199/mo
semaglutide

Standing $199-$249/mo by dose; $50-off intro coupon ORALGLP50.

Drops / sublingual (lowest dose)Compounded · oral
$249/mo
tirzepatide

Standing $249-$299/mo by dose; $50-off intro coupon FIRST50. Plan funnel: $199/mo monthly down to $159/mo annual.

Troche / lozengeCompounded · oral
$249/mo
semaglutide

Standing $249-$299/mo; $50-off intro coupon TROCHE50.

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What’s included

1st Optimal

Inclusions not disclosed.

Try Ageless

What the monthly price covers

Medication

Included

Provider visits

Not disclosed

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Try Ageless

6.9/10

Value25%

6.5A
vs
B
6.0

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
7.8

Accessibility10%

6.5A
vs
B
6.0

Support10%

7.4A
vs
B
6.9

Features & Coverage

Feature1st OptimalTry Ageless
Starting Price$119/mo
Features8 features5 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Try Ageless

Try Ageless is a longevity and metabolic-health telehealth platform offering compounded semaglutide and tirzepatide in three forms — injection, troche, and sublingual drops — the broadest format range in our directory. It's LegitScript Certified with aggressive introductory pricing across all five products. Semaglutide injection starts at $119/month, one of the lowest entry prices we track.

Read our full Try Ageless review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Try Ageless

What we like

  • LegitScript Certified
  • Three compounded forms offered: injection, troche, and sublingual drops — the broadest form-factor range we track
  • Publishes the FDA compounded-medication disclaimer
  • Among the lowest intro prices we track — semaglutide injection at $119/mo
  • Delaware corporate address disclosed
  • Longevity and metabolic-health positioning

Watch-outs

  • Only introductory pricing shown — refill/maintenance prices not disclosed and may step up
  • Pharmacy partner not named (only 'state-licensed pharmacies')
  • States-served list not provided — availability depends on your state
  • Named medical director not disclosed
  • 503A vs 503B compounding designation not specified
  • Compounded oral forms (drops, troche) have a weaker evidence base than injectable

Our Verdict

Winner: Try Ageless

Try Ageless edges out 1st Optimal with a higher overall score of 6.9/10 and is particularly strong for lowest-tier compounded GLP-1 in injection, troche and sublingual forms. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose Try Ageless if…

You want lowest-tier compounded GLP-1 in injection, troche and sublingual forms and a starting price around $119/mo.

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7.3

Sunlight

Compounded GLP-1 with unlimited telehealth visits and free shipping

7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

8.3

Found

Mainstream telehealth GLP-1 access

1st Optimal vs Try Ageless: FAQ

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