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1st Optimal vs This Gen Wellness

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
This Gen Wellness logo

This Gen Wellness

6.2
★★★☆☆3.1/5

Best for: New Yorkers who want a required live video visit rather than a form-only intake

Visit This Gen Wellness

1st Optimal and This Gen Wellness are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal edges ahead overall (6.7 vs 6.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

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Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

This Gen Wellness

6.2/10

Value25%

6.5A
vs
B
5.5

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

6.5A
vs
B
6.5

Trust & Safety15%

6.5A
vs
B
7.0

Accessibility10%

6.5A
vs
B
3.5

Support10%

7.4A
vs
B
7.0

Features & Coverage

Feature1st OptimalThis Gen Wellness
Starting Price
Features8 features8 features
States AvailableNot disclosed1
Compounded
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About This Gen Wellness

This Gen Wellness is a New York-only telehealth practice operated by ThisGen, LLC, offering medically supervised weight loss alongside hormone therapy and ED care. Its distinguishing feature is process: every prescription follows a synchronous live audio-video visit with a New York-licensed clinician, never the intake form alone. The weight-loss program may include semaglutide or tirzepatide. Prices are not published — cost is disclosed only after a clinician reviews your assessment.

Read our full This Gen Wellness review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

This Gen Wellness

What we like

  • Requires a synchronous live audio-video visit with a New York-licensed clinician — prescriptions are never issued from the intake form alone
  • Assessment and clinician review are free; you only pay if treatment is prescribed and you choose to proceed
  • Names its legal entity (ThisGen, LLC) and specifies New York governing law in its terms
  • No long-term contracts — plans can be paused or stopped
  • The same clinician follows your care, with ongoing secure messaging between visits
  • Publishes a dated FAQ covering side effects, emergencies and data deletion

Watch-outs

  • Publishes no prices at all — 'We don't list flat prices on the website'; cost is disclosed only after a clinician reviews your assessment
  • Serves New York only — 'we currently operate exclusively for patients located in New York'
  • Dispensing pharmacies are not named, only described as 'licensed U.S. pharmacies'
  • Does not state whether its semaglutide and tirzepatide are compounded or brand-name
  • Does not bill insurance; verifying any reimbursement is the patient's responsibility
  • No LegitScript certification or pharmacy accreditation displayed
  • Legal entity is registered in San Antonio, Texas while care is limited to New York

Our Verdict

Winner: 1st Optimal

1st Optimal edges out This Gen Wellness with a higher overall score of 6.7/10 and is particularly strong for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program. This Gen Wellness remains a solid alternative, especially if you're looking for New Yorkers who want a required live video visit rather than a form-only intake.

Choose 1st Optimal if…

You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose This Gen Wellness if…

You want New Yorkers who want a required live video visit rather than a form-only intake.

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8.3

Found

Mainstream telehealth GLP-1 access

7.4

Breeze Meds

Compounded GLP-1 access with named prescribers and 4-pharmacy network

8.1

GobyMeds

Budget-conscious shoppers

1st Optimal vs This Gen Wellness: FAQ

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