1st Optimal vs The Edit
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
The Edit
Best for: flat per-dose pricing from a brand that names its pharmacy and prescribing practice
Visit The Edit →1st Optimal and The Edit are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, The Edit starts at $209/mo, and The Edit edges ahead overall (7.3 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
The Edit
$109 first order via an automatically applied $100-off promotion, then $209/month. Prepay tiers are billed once upfront: 3 months $575 ($192/mo), 6 months $1,065 ($178/mo).
$209 first order, then $309/month standing rate.
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
The Edit
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
The Edit
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | The Edit |
|---|---|---|
| Starting Price | — | $209/mo |
| Features | ✓8 features | 7 features |
| States Available | Not disclosed | 50 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About The Edit
The Edit is a clinician-led telehealth brand from The Edit Health LLC, a Texas management services organization based in Austin. It sells compounded semaglutide and tirzepatide for weight loss alongside NAD+, sermorelin, glutathione and GHK-Cu protocols. Prescribing is handled by an affiliated independent practice, Arora Health & Aesthetics, and prescriptions are dispensed by named partner pharmacy The Pharmacy Hub in Miami. Prices are published openly on every treatment page, there is no card on file to begin, and the site runs in both English and Spanish.
Read our full The Edit review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
The Edit
What we like
- Publishes a real LegitScript seal (ID 51177190) and names both its dispensing pharmacy and its prescribing medical practice.
- Charges the same price at every dose, so titrating up does not raise the monthly cost.
- Nothing is charged to start, with no card on file, and a full refund if a clinician decides treatment is not appropriate.
- Prices are published on every treatment page rather than gated behind intake, in both English and Spanish.
Watch-outs
- The $209/mo standing semaglutide rate sits above the market median; the $109 headline is a first-order promo, not the ongoing price.
- The 3- and 6-month rates are billed once upfront ($575 and $1,065), not as a lower monthly charge.
- Terms claim all 50 states but also say availability is verified during consultation and may vary, so coverage is not guaranteed.
- Cancellation ends at the close of the current billing period and part-used periods are not pro-rated or refunded.
Our Verdict
The Edit edges out 1st Optimal with a higher overall score of 7.3/10 and is particularly strong for flat per-dose pricing from a brand that names its pharmacy and prescribing practice. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program.
Choose The Edit if…
You want flat per-dose pricing from a brand that names its pharmacy and prescribing practice and a starting price around $209/mo.
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Get started →1st Optimal vs The Edit: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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