1st Optimal vs TeleSlim Clinic
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →TeleSlim Clinic
Best for: md-supervised glp-1 care with transparent membership pricing in the midwest and select states
Visit TeleSlim Clinic →1st Optimal and TeleSlim Clinic are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, TeleSlim Clinic starts at $99/mo, and TeleSlim Clinic edges ahead overall (7.2 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
TeleSlim Clinic
99 dollars per month clinical membership covering physician oversight and GLP-1 prescribing; compounded medication dispensed via pharmacy may be an added cost
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What’s included
1st Optimal
Inclusions not disclosed.
TeleSlim Clinic
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Billed separately
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
TeleSlim Clinic
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | TeleSlim Clinic |
|---|---|---|
| Starting Price | — | $99/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 6 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About TeleSlim Clinic
TeleSlim Clinic is a physician-led telehealth weight-loss practice run by board-certified obesity-medicine doctors, prescribing GLP-1 and GIP medications (semaglutide and tirzepatide). Care is sold as a clinical membership: a 99-dollar initial visit (promo, normally 199) and a 99-dollar per month plan, with 3-month (269), 6-month (499), and annual (899) options. The monthly fee covers physician oversight and prescribing; medication is dispensed through a named pharmacy. LegitScript certified. Serves Illinois plus telemedicine in Texas, Colorado, Michigan, Pennsylvania, and Arizona.
Read our full TeleSlim Clinic review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
TeleSlim Clinic
What we like
- Board-certified obesity-medicine physicians oversee care
- LegitScript certified with a named dispensing pharmacy (Rush Pharmacy)
- Transparent, low monthly membership pricing with multi-month plans
Watch-outs
- Medication cost is separate from the 99-dollar membership and not clearly published
- Available in only six states
Our Verdict
TeleSlim Clinic edges out 1st Optimal with a higher overall score of 7.2/10 and is particularly strong for md-supervised glp-1 care with transparent membership pricing in the midwest and select states. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose TeleSlim Clinic if…
You want md-supervised glp-1 care with transparent membership pricing in the midwest and select states and a starting price around $99/mo.
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Sesame Care
Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
From $25/mo
Get started →Try Ageless
Lowest-tier compounded GLP-1 in injection, troche and sublingual forms
From $119/mo
Get started →Sunlight
Compounded GLP-1 with unlimited telehealth visits and free shipping
From $159/mo
Get started →1st Optimal vs TeleSlim Clinic: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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