Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

1st Optimal vs TeleFirst Med

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

6.7

1st Optimal

Best for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program
★★★☆☆3.4
Semaglutide GLP-1Tirzepatide GLP-1Oral tablet optionAt-home lab testing
Visit 1st Optimal
6.3

TeleFirst Med

Best for TX or NC patients who want a brand-name (not compounded) GLP-1 prescription via a $120 telehealth visit
★★★☆☆3.2
Brand-name GLP-1Not compounded$120 telehealth evaluationFill at your pharmacy
Visit TeleFirst Med

Side-by-Side Comparison

Feature1st OptimalTeleFirst Med
Overall Score6.7/106.3/10
Starting Price
Editorial Rating3.4 ★ /53.2 ★ /5
Features8 features8 features
States Available02
Compounded
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

TeleFirst Med

What we like

  • Prescribes real brand-name GLP-1 (e.g. Ozempic/Wegovy), not compounded — appealing if you specifically want FDA-approved branded medication
  • Simple $120 telehealth evaluation with a licensed doctor; no insurance hassle and no prior authorization
  • You fill the prescription at your own regular pharmacy rather than waiting on a mail-order compounding pharmacy
  • Also a general telehealth clinic (urgent care, chronic-condition management) if you want broader care

Watch-outs

  • Only Texas and North Carolina are confirmed — not available nationwide
  • The $120 is an evaluation fee; the brand-name medication is billed separately at your pharmacy and can be expensive without insurance
  • Small practice (about 500 patients) with limited public detail on its clinicians and program
  • No compounded or lower-cost medication option, and no medication pricing is published

Our Verdict

Winner: 1st OptimalScore: 6.7/10

1st Optimal edges out TeleFirst Med with a higher overall score of 6.7/10 and is particularly strong for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program. TeleFirst Med remains a solid alternative, especially if you're looking for TX or NC patients who want a brand-name (not compounded) GLP-1 prescription via a $120 telehealth visit.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Related comparisons

Continue exploring 1st Optimal and TeleFirst Med head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.