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1st Optimal vs TeleDocs360

Name: 1st Optimal
Brand: 1st Optimal
Availability: OnlineOnly

An in-depth comparison of two leading GLP-1 Providers

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6.7

1st Optimal

Best for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program

★★★☆☆3.4

Semaglutide GLP-1Tirzepatide GLP-1Oral tablet optionAt-home lab testing

Visit 1st Optimal →

6.6

TeleDocs360

Best for Cash-pay patients wanting compounded GLP-1 options with transparent base pricing

★★★☆☆3.3

Starting at $399/mo

Compounded semaglutideCompounded tirzepatideOral semaglutide optionPhentermine available

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Side-by-Side Comparison

Feature	1st Optimal	TeleDocs360
Overall Score	✓6.7/10	6.6/10
Starting Price	—	$399/mo
Editorial Rating	✓3.4 ★ /5	3.3 ★ /5
Features	8 features	8 features
States Available	0	0
Compounded	—	✓ Yes
Brand Name	—	—
FSA/HSA Accepted	—	✓ Yes
FDA Warnings	None	None

Pros & Cons

1st Optimal

Pros

✓Offers both semaglutide and tirzepatide with injectable and oral formats
✓Functional-medicine approach with at-home labs and blood-work interpretation
✓Unlimited coaching and ongoing support included
✓No long-term contracts
✓Board-certified doctors and nurse practitioners referenced

Cons

✗No public monthly pricing disclosed
✗No published state availability list
✗Compounded vs branded sourcing not clarified on site
✗Pricing only revealed after quiz or consultation

TeleDocs360

Pros

✓Transparent $399/month base pricing for standard dosing
✓Multiple GLP-1 options including injectable and oral semaglutide
✓Cash-pay model with HSA/FSA card acceptance
✓Fast online intake and 24-hour prescription approval
✓Cancel anytime between shipments

Cons

✗Compounded-only; no FDA-approved branded options
✗No published state availability list
✗No individual provider credentials or board certifications shown
✗Higher doses increase cost

Our Verdict

Winner: 1st OptimalScore: 6.7/10

1st Optimal edges out TeleDocs360 with a higher overall score of 6.7/10 and is particularly strong for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program. TeleDocs360 remains a solid alternative, especially if you're looking for Cash-pay patients wanting compounded GLP-1 options with transparent base pricing.

Get Started with 1st Optimal →Get Started with TeleDocs360 →

Glossary references

Key terms in this article, linked to their canonical definitions.

Semaglutide · Drugs and brands
Tirzepatide · Drugs and brands
Compounded GLP-1 · Pharmacy and drug forms
503A pharmacy · Pharmacy and drug forms
PCAB accreditation · Pharmacy and drug forms
Prior authorization (PA) · Insurance and regulatory
Off-label use · Insurance and regulatory
FDA Drug Shortage List · Insurance and regulatory

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