Best Alternatives to 1st Optimal

1st Optimal doesn't post a standard cash price, so we led with CoreAge Rx and 11 other vetted alternatives compared by price, medication, and state coverage.

← Read our full 1st Optimal review

You're comparing against

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1st Optimal

6.7

Best for: GLP-1 therapy within a lab-driven functional-medicine program

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Offers: SemaglutideCoverage: Check intakeLegitScript: Not on fileFDA record: No warning letters on file

Alternatives to 1st Optimal, compared

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Top alternatives to 1st Optimal

  1. 8.3

    CoreAge RxAffiliate partner

    Semaglutide, Tirzepatide · 50 states · LegitScript verified

    $79/mo

    semaglutide

    No published price. One of the two doesn't publish a standard price.
    Get started
  2. 8.3

    CollectiveAffiliate partner

    Semaglutide, Tirzepatide · 44 states

    $59/mo

    semaglutide · + separate membership

    No published price. One of the two doesn't publish a standard price.
    Get started
  3. 8.3

    FoundAffiliate partner

    Semaglutide, Tirzepatide, Orforglipron · 50 states

    $169/mo

    semaglutide · on a 12-month prepaid plan

    No published price. One of the two doesn't publish a standard price.
    Get started
  4. 8.2

    Enhance MDAffiliate partner

    Semaglutide, Tirzepatide · 39 states

    $169/mo

    tirzepatide

    No published price. One of the two doesn't publish a standard price.
    Get started
  5. 8.2

    GalaAffiliate partner

    Tirzepatide, Semaglutide · 50 states · LegitScript verified

    $149/mo

    tirzepatide

    No published price. One of the two doesn't publish a standard price.
    Get started
  6. 8.1

    bmiMDAffiliate partner

    Semaglutide, Tirzepatide · 50 states

    $99/mo

    semaglutide

    No published price. One of the two doesn't publish a standard price.
    Get started

More alternatives to 1st Optimal

  1. 8.1

    RxSpan MDAffiliate partner

    Semaglutide, Tirzepatide · 50 states · LegitScript verified

    $249/mo

    semaglutide

    No published price. One of the two doesn't publish a standard price.
    Get started
  2. 8.1

    OakAffiliate partner

    Semaglutide, Tirzepatide · 48 states

    $200/mo

    semaglutide · $133/mo on a 3-month plan

    No published price. One of the two doesn't publish a standard price.
    Get started
  3. 8.0

    Sesame CareAffiliate partner

    State list not published

    $149/mo

    brand Wegovy pill / Rybelsus

    No published price. One of the two doesn't publish a standard price.
    Get started
  4. 8.0

    ShedRxAffiliate partner

    Semaglutide, Tirzepatide, Orforglipron · State list not published

    $149/mo

    semaglutide (pill or injection) · + separate membership

    No published price. One of the two doesn't publish a standard price.
    Get started
  5. 8.0

    Strut HealthAffiliate partner

    Semaglutide, Tirzepatide · 49 states · LegitScript verified · 1 FDA warning letter

    $99/mo

    oral compounded semaglutide

    No published price. One of the two doesn't publish a standard price.
    Get started
  6. 7.9

    GobyMedsAffiliate partner

    Semaglutide, Tirzepatide · 50 states · LegitScript verified

    $169/mo

    semaglutide

    No published price. One of the two doesn't publish a standard price.
    Get started

Savings are shown only when both providers list the same medication at a standing price, with no prepay or separate membership, compared over a year. Each price is the provider’s headline published price, with its drug and plan terms underneath.

Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

Why look for alternatives to 1st Optimal?

  • From our review

    No public monthly pricing disclosed

  • From our review

    No published state availability list

  • Verification

    No LegitScript verification on file

  • Coverage

    No published state list; confirm yours at signup

Frequently Asked Questions

Our review of 1st Optimal notes two recurring drawbacks: No public monthly pricing disclosed; No published state availability list. 1st Optimal does not carry a LegitScript verification badge in our records — several alternatives below do, if third-party pharmacy verification matters to you. The picks above were selected on overall score, value, and experience — one may fit your situation better.
Yes — switching telehealth providers is common and low-risk as long as the new provider is reputable and a licensed clinician oversees your care. You'll complete a quick intake, and the clinician reviews your history and current dose before continuing treatment. Never stop or change your dose on your own; let the prescribing clinician guide any transition.
Pricing varies across providers. Each alternative shows its starting price so you can compare — costs change with medication, dose, and active promotions, so confirm the ongoing rate before you commit.
In most cases you start fresh with the new provider rather than transferring a compounded prescription directly — the new clinician writes a new prescription after reviewing your history. Keep a record of your current medication, dose, and pharmacy; it makes the new intake faster and helps the clinician continue you at the right dose.
You'll complete a new online intake with any alternative, since each provider's clinicians need to evaluate you directly. 1st Optimal's own intake does require labs, so if a new alternative doesn't, that's one fewer step switching over.
Our Top Pick above is the closest match based on value, effectiveness, experience, trust, accessibility, and support. If you want a near drop-in replacement, start there — then use the comparison below to weigh price and medication type against your priorities.

Key terms, explained

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