Telos Rx vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
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Telos Rx
Best for Needle-free and microdosed compounded GLP-1 options with lab-monitored careStarting at $49/mo
Enhance MD
Best for lab-monitored compounded GLP-1 with mandatory video visitStarting at $212/mo
Side-by-Side Comparison
| Feature | Telos Rx | Enhance MD |
|---|---|---|
| Overall Score | 8.2/10 | ✓8.6/10 |
| Starting Price | ✓$49/mo | $212/mo |
| Editorial Rating | 4.1 ★ /5 | ✓4.3 ★ /5 |
| Features | ✓8 features | 6 features |
| States Available | 0 | ✓39 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | None | None |
Pros & Cons
Telos Rx
What we like
- Multiple GLP-1 modalities: compounded semaglutide and tirzepatide injections plus needle-free sublingual and microdosed tirzepatide
- Provider-led dose adjustments and lab monitoring as your protocol changes
- Free discreet, temperature-controlled shipping (no Telos branding on the outside)
- FSA/HSA eligible and cancel anytime in one click
- Trustpilot rating of 4.9; full compliance suite published (Privacy, Terms, HIPAA, Shipping & returns)
- Integrated care team spanning weight loss, longevity, recovery, and sexual health (peptide-led)
Watch-outs
- Headline pricing is 'first month low as' intro pricing (semaglutide $49, tirzepatide $99) — ongoing monthly cost is higher and shown during intake
- Compounded medications are not FDA-approved (the site discloses this) — not brand Wegovy, Ozempic, Zepbound, or Mounjaro
- Compounding pharmacy partner is not named
- State-availability list is not published
- No LegitScript certification displayed
Enhance MD
What we like
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- Unlimited clinician messaging and dose-adjustment support included
Watch-outs
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- No insurance accepted — cash pay, HSA/FSA eligible
- Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out Telos Rx with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. Telos Rx remains a solid alternative, especially if you're looking for Needle-free and microdosed compounded GLP-1 options with lab-monitored care.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.