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Nova MD vs Enhance MD

An in-depth comparison of two leading GLP-1 Providers

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7.2

Nova MD

Best for lowest 3-month compounded pricing with an explicit microdose program
★★★★☆3.6

Starting at $125/mo

CompoundedMicrodose OptionsSemaglutideTirzepatide
Visit Nova MD →
8.6

Enhance MD

Best for lab-monitored compounded GLP-1 with mandatory video visit
★★★★☆4.3

Starting at $49/mo

CompoundedSemaglutideTirzepatideVideo Visit
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Side-by-Side Comparison

FeatureNova MDEnhance MD
Overall Score7.2/10✓8.6/10
Starting Price$125/mo✓$49/mo
Editorial Rating3.6 ★ /5✓4.3 ★ /5
Features✓8 features6 features
States Available0✓39
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted✓ Yes—
FDA WarningsNoneNone

Pros & Cons

Nova MD

Pros

  • ✓On-page pricing published for all four SKUs (semaglutide and tirzepatide, 1- and 3-month)
  • ✓$125/mo semaglutide and $199/mo tirzepatide 3-month plans rank among the cheapest in the market
  • ✓$50 off first tirzepatide order shown publicly
  • ✓Explicit microdose / low-dose program for both semaglutide and tirzepatide
  • ✓Broader menu (sermorelin, NAD+, glutathione, enclomiphene) for longevity alongside GLP-1
  • ✓FSA/HSA eligible and cancel-anytime billing with same-day doctor review

Cons

  • ✗Legal entity name and state of incorporation not disclosed
  • ✗Compounding pharmacy not named — only 'accredited facilities'
  • ✗LegitScript certification not confirmed (only 'Licensed US Providers' claims)
  • ✗Per-state availability not listed
  • ✗Compounded only — no brand-name Wegovy, Zepbound, Mounjaro, or Ozempic
  • ✗Lab work and ongoing monitoring aren't clearly addressed
  • ✗Patient count (1,241+) is an unverified marketing claim

Enhance MD

Pros

  • ✓Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
  • ✓Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
  • ✓Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
  • ✓Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
  • ✓Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
  • ✓Unlimited clinician messaging and dose-adjustment support included

Cons

  • ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
  • ✗Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
  • ✗Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
  • ✗No insurance accepted — cash pay, HSA/FSA eligible
  • ✗Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost

Our Verdict

Winner: Enhance MDScore: 8.6/10

Enhance MD edges out Nova MD with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. Nova MD remains a solid alternative, especially if you're looking for lowest 3-month compounded pricing with an explicit microdose program.

Get Started with Nova MD →Get Started with Enhance MD →

Glossary references

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.